Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CTSG | P08311 | 1/20 | 0.51 |
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490691 | 0.87 | CTSG (0.56) | KMT2AMEN1ALDH1A1CTSGCMA1 | |
| SCHEMBL7885276 | 0.86 | CTSG (0.55) | KMT2AMEN1ALDH1A1CTSGCMA1 | |
| SCHEMBL7333227 | 0.85 | CA12 (0.54) | KMT2AMEN1ALDH1A1CTSGCMA1 | |
| SCHEMBL7637117 | 0.85 | MTNR1A (0.55) | KMT2AMEN1ALDH1A1KDM4ETAAR1 | |
| SCHEMBL10714737 | 0.84 | KMT2A (0.55) | KMT2AMEN1ALDH1A1CA12CA1 | |
| SCHEMBL4684922 | 0.83 | CA12 (0.51) | KMT2AMEN1ALDH1A1CTSGCMA1 | |
| SCHEMBL2397498 | 0.83 | CTSG (0.52) | KMT2AMEN1ALDH1A1CTSGCMA1 | |
| SCHEMBL4684928 | 0.83 | CA12 (0.55) | KMT2AMEN1ALDH1A1CTSGCMA1 | |
| SCHEMBL612449 | 0.81 | FFAR4 (0.51) | KMT2AMEN1ALDH1A1CTSGCMA1 | |
| SCHEMBL6112724 | 0.80 | PPARA (0.52) | KMT2AMEN1ALDH1A1CTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534536-B1 | Process for the preparation of 2-amino-5,6-dimethoxy-tetralin | ZAMBON SPA (IT) | 1996-01-31 | — | — | EP | disclosed |
| US-5221770-A | PROCESS FOR THE PREPARATION OF 2-AMINO-5,6-DIMETHOXY-TETRALIN | ZAMBON GROUP S.P.A. (IT) | 1993-06-22 | — | — | US | disclosed |
| EP-0534536-A2 | Process for the preparation of 2-amino-5,6-dimethoxy-tetralin | ZAMBON GROUP S.p.A. (IT) | 1993-03-31 | — | — | EP | disclosed |