Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 4/20 | 0.52 |
| ▸ | HTR2A | P28223 | 4/20 | 0.52 |
| ▸ | HTR2C | P28335 | 3/20 | 0.52 |
| ▸ | HTR1D | P28221 | 2/20 | 0.52 |
| ▸ | HTR1B | P28222 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HTR1E | P28566 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28237490 | 0.82 | SLC6A4 (0.59) | SLC6A4HTR1AHTR2AHTR2CHTR1D | |
| SCHEMBL7001306 | 0.82 | HTR2A (0.69) | SLC6A4HTR1AHTR2AHTR2CHTR1D | |
| SCHEMBL7004071 | 0.82 | HTR2A (0.69) | SLC6A4HTR1AHTR2AHTR2CHTR1D | |
| SCHEMBL7889427 | 0.82 | HTR2A (0.69) | SLC6A4HTR1AHTR2AHTR2CHTR1D | |
| SCHEMBL23317711 | 0.81 | HTR2A (0.60) | SLC6A4HTR1AHTR2AHTR2CHTR1D | |
| SCHEMBL20103761 | 0.81 | SLC6A4 (0.54) | SLC6A4HTR1AHTR2AHTR2CHTR1D | |
| SCHEMBL7004146 | 0.80 | HTR2A (0.71) | SLC6A4HTR1AHTR2AHTR2CHTR1D | |
| SCHEMBL28236251 | 0.80 | SLC6A4 (0.59) | SLC6A4HTR1AHTR2AHTR2CHTR1D | |
| SCHEMBL9289534 | 0.79 | ALOX12 (0.43) | SLC6A4HTR2AALOX12ALDH1A1KDM4E | |
| SCHEMBL7388575 | 0.79 | SLC6A4 (0.62) | SLC6A4HTR1AHTR2AHTR2CHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530019-A | FOR TREATMENT OF PROSTATE GLAND DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0648208-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994022821-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |