Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 10/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960097 | 0.96 | GPR3 (0.39) | KCNJ1KCNH2GPR3DRD2SLC6A2 | |
| SCHEMBL8959979 | 0.94 | GPR3 (0.41) | KCNJ1KCNH2GPR3DRD2SLC6A2 | |
| SCHEMBL8960004 | 0.94 | GPR3 (0.41) | KCNJ1KCNH2GPR3DRD2SLC6A2 | |
| SCHEMBL8959807 | 0.94 | GPR3 (0.41) | KCNJ1KCNH2GPR3DRD2SLC6A2 | |
| SCHEMBL8960023 | 0.94 | GPR3 (0.41) | KCNJ1KCNH2GPR3DRD2SLC6A2 | |
| SCHEMBL8959913 | 0.94 | GPR3 (0.41) | KCNJ1KCNH2GPR3DRD2SLC6A2 | |
| SCHEMBL8959786 | 0.94 | GPR3 (0.41) | KCNJ1KCNH2GPR3DRD2SLC6A2 | |
| SCHEMBL8960101 | 0.94 | GPR3 (0.41) | KCNJ1KCNH2GPR3DRD2SLC6A2 | |
| SCHEMBL8960183 | 0.91 | KCNJ1 (0.40) | KCNJ1KCNH2HTR2AHTR2C | |
| SCHEMBL8960053 | 0.85 | KCNJ1 (0.36) | KCNJ1KCNH2HTR2AHTR2CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510456-A | Bridged cyclic arleneethylene polymers | SHOWA DENKO K. K. (JP) | 1996-04-23 | — | — | US | disclosed |