Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 11/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960183 | 0.88 | KCNJ1 (0.40) | KCNJ1KCNH2HTR2AHTR2CHTR2B | |
| SCHEMBL8959964 | 0.85 | KCNJ1 (0.39) | KCNJ1KCNH2NPC1MAPK1RAB9A | |
| SCHEMBL8960097 | 0.84 | GPR3 (0.39) | KCNJ1KCNH2ALDH1A1LMNAHTR2A | |
| SCHEMBL8960004 | 0.83 | GPR3 (0.41) | KCNJ1KCNH2ALDH1A1LMNAHTR2A | |
| SCHEMBL8959913 | 0.83 | GPR3 (0.41) | KCNJ1KCNH2ALDH1A1LMNAHTR2A | |
| SCHEMBL8959786 | 0.83 | GPR3 (0.41) | KCNJ1KCNH2ALDH1A1LMNAHTR2A | |
| SCHEMBL8959979 | 0.83 | GPR3 (0.41) | KCNJ1KCNH2ALDH1A1LMNAHTR2A | |
| SCHEMBL8960101 | 0.83 | GPR3 (0.41) | KCNJ1KCNH2ALDH1A1LMNAHTR2A | |
| SCHEMBL8960023 | 0.83 | GPR3 (0.41) | KCNJ1KCNH2ALDH1A1LMNAHTR2A | |
| SCHEMBL8960014 | 0.78 | METAP1 (0.39) | MAPTGAAALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510456-A | Bridged cyclic arleneethylene polymers | SHOWA DENKO K. K. (JP) | 1996-04-23 | — | — | US | disclosed |