Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10954756 | 0.87 | OPRL1 (0.64) | OPRL1KDM4EKMT2AGAAUSP2 | |
| SCHEMBL5242779 | 0.87 | OPRL1 (0.67) | OPRL1KDM4EKMT2APOLBCYP3A4 | |
| Hydrochloric Acid SCHEMBL11397626 | 0.86 | OPRL1 (0.63) | OPRL1KDM4EKMT2APOLBGAA | |
| SCHEMBL8751528 | 0.86 | KDM4E (0.56) | OPRL1KDM4EKMT2APOLBCCR3 | |
| Hydrochloric Acid SCHEMBL10750648 | 0.85 | POLB (0.68) | OPRL1KDM4EKMT2APOLBCYP3A4 | |
| SCHEMBL4778246 | 0.84 | OPRL1 (0.78) | OPRL1POLBGAACCR3OPRM1 | |
| SCHEMBL19330902 | 0.83 | KDM4E (0.56) | OPRL1KDM4EKMT2APOLBCYP3A4 | |
| SCHEMBL8751541 | 0.83 | KDM4E (0.56) | OPRL1KDM4EKMT2APOLBGAA | |
| SCHEMBL11450342 | 0.82 | OPRM1 (0.61) | OPRL1KDM4EKMT2AUSP2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11437813 | 0.82 | OPRM1 (0.60) | OPRL1KDM4EKMT2APOLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691956-A1 | 3-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE DERIVATIVES AS SEDATIVES | LABORATOIRE L. LAFON (FR) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022827-A1 | 3-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE DERIVATIVES AS SEDATIVES | LABORATOIRE L. LAFON (FR) | 1994-10-13 | — | — | WO | disclosed |