Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CCR3 | P51677 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 6/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5242779 | 0.90 | OPRL1 (0.67) | KDM4EKMT2AOPRL1POLBCCR3 | |
| Hydrochloric Acid SCHEMBL10750648 | 0.89 | POLB (0.68) | KDM4EKMT2AOPRL1POLBCCR3 | |
| SCHEMBL8751541 | 0.86 | KDM4E (0.56) | KDM4EKMT2AOPRL1POLBCCR3 | |
| SCHEMBL19330902 | 0.86 | KDM4E (0.56) | KDM4EKMT2AOPRL1POLBCCR3 | |
| SCHEMBL8960154 | 0.86 | OPRL1 (0.57) | KDM4EKMT2AOPRL1POLBCCR3 | |
| Hydrochloric Acid SCHEMBL9310920 | 0.85 | KDM4E (0.58) | KDM4EKMT2AOPRL1POLBCCR3 | |
| SCHEMBL4265747 | 0.83 | CYP2D6 (0.58) | KDM4EKMT2AOPRL1POLBCCR3 | |
| SCHEMBL6110923 | 0.83 | OPRL1 (0.79) | KMT2AOPRL1POLBCCR3DRD2 | |
| SCHEMBL29017359 | 0.83 | CACNA1G (0.56) | KMT2APOLBDRD2CYP2D6SIGMAR1 | |
| SCHEMBL8969668 | 0.82 | KDM4E (0.60) | KDM4EKMT2AOPRL1POLBCCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766562-A1 | THERAPEUTICAL COMPOSITIONS COMPRISING 3-PHENYL-3-HYDROXYPIPERIDINES | LABORATOIRE L. LAFON (FR) | 1997-04-09 | — | — | EP | disclosed |
| EP-0691956-A1 | 3-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE DERIVATIVES AS SEDATIVES | LABORATOIRE L. LAFON (FR) | 1996-01-17 | — | — | EP | disclosed |
| WO-1996000064-A1 | THERAPEUTICAL COMPOSITIONS COMPRISING 3-PHENYL-3-HYDROXYPIPERIDINES | LABORATOIRE L. LAFON (FR) | 1996-01-04 | — | — | WO | disclosed |
| WO-1994022827-A1 | 3-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE DERIVATIVES AS SEDATIVES | LABORATOIRE L. LAFON (FR) | 1994-10-13 | — | — | WO | disclosed |