Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3919900 | 0.87 | VCAM1 (0.60) | POLBMCOLN3ALDH1A1MAPK1LMNA | |
| SCHEMBL6038599 | 0.85 | POLB (0.52) | POLBMCOLN3ALDH1A1MAPK1LMNA | |
| SCHEMBL3906545 | 0.85 | POLB (0.52) | POLBMCOLN3ALDH1A1MAPK1LMNA | |
| SCHEMBL540736 | 0.85 | POLB (0.52) | POLBMCOLN3ALDH1A1MAPK1LMNA | |
| SCHEMBL6038596 | 0.85 | POLB (0.52) | POLBMCOLN3ALDH1A1MAPK1LMNA | |
| SCHEMBL12727381 | 0.84 | POLB (0.51) | POLBMCOLN3ALDH1A1MAPK1LMNA | |
| Water SCHEMBL3157352 | 0.84 | POLB (0.51) | POLBMCOLN3ALDH1A1MAPK1LMNA | |
| Hydrochloric Acid SCHEMBL27447923 | 0.84 | POLB (0.51) | POLBMCOLN3ALDH1A1MAPK1LMNA | |
| SCHEMBL11091009 | 0.83 | POLB (0.60) | POLBMCOLN3ALDH1A1MAPK1LMNA | |
| SCHEMBL14519881 | 0.83 | POLB (0.50) | POLBMCOLN3ALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585373-A | STABILITY, LOWER TOXICITY | TAIHO PHARMACEUTICAL CO., LTD (JP) | 1996-12-17 | — | — | US | disclosed |