Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CDC25A | P30304 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.52 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268031 | 1.00 | LMNA (0.54) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL1648522 | 1.00 | LMNA (0.54) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL2370673 | 1.00 | LMNA (0.54) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL15566127 | 1.00 | LMNA (0.54) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL5251441 | 1.00 | LMNA (0.54) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL9073605 | 1.00 | LMNA (0.54) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL6384775 | 0.94 | MEN1 (0.53) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL7515687 | 0.94 | PLA2G1B (0.49) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL9005240 | 0.92 | LMNA (0.46) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL18554720 | 0.92 | LMNA (0.46) | LMNAESR1ADORA3CDC25AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040694-A1 | CARBONOTHIOATE PHOSPHOLIPID ANALOGS AS SUBSTRATE OF PHOSPHOLIPASES AND LIPASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0691852-A1 | PRODRUGS WITH ENHANCED PENETRATION INTO CELLS | D-PHARM, LTD. (IL) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022483-A2 | PRODRUGS WITH ENHANCED PENETRATION INTO CELLS | D-PHARM, LTD. (IL) | 1994-10-13 | — | — | WO | disclosed |