Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805717 | 1.00 | LMNA (0.46) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL18554720 | 1.00 | LMNA (0.46) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL6268031 | 0.92 | LMNA (0.54) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL5251441 | 0.92 | LMNA (0.54) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL9073605 | 0.92 | LMNA (0.54) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL1648522 | 0.92 | LMNA (0.54) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL8960305 | 0.92 | LMNA (0.54) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL15566127 | 0.92 | LMNA (0.54) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL2370673 | 0.92 | LMNA (0.54) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL7116939 | 0.87 | SMN1; SMN2 (0.52) | LMNAESR1ADORA3CDC25AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11344498-B2 | Compositions and methods for on-demand high-efficiency triggerable anesthesia | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-05-31 | — | — | US | disclosed |
| US-20190307703-A1 | MULTI-FUNCTIONAL NANOPARTICLES FOR VACCINATION | ZHANG YUAN (US) | 2019-10-10 | — | — | US | disclosed |
| US-20190307901-A1 | METHOD FOR ENHANCED NUCLEIC ACID TRANSFECTION USING A PEPTIDE | ZHANG YUAN (US) | 2019-10-10 | — | — | US | disclosed |
| US-20190070115-A1 | Compositions and Methods for On-Demand High-Efficiency Triggerable Anesthesia | THE CHILDREN'S MEDICAL CENTER CORPORATION | 2019-03-07 | — | — | US | disclosed |
| WO-2017062875-A1 | COMPOSITIONS AND METHODS FOR ON-DEMAND HIGH-EFFICIENCY TRIGGERABLE ANESTHESIA | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2017-04-13 | — | — | WO | disclosed |
| CN-101198398-B | Membrane for filtering water | AQUAPORIN APS (DK) | 2012-10-31 | — | — | CN | disclosed |
| CN-102145259-A | Membrane for filtering of water | AQUAPORIN AS (DK) | 2011-08-10 | — | — | CN | disclosed |
| CN-101198398-A | Membrane for filtering water | AQUAPORIN APS (DK) | 2008-06-11 | — | — | CN | disclosed |
| US-5516662-A | Process for the preparation of headgroup-modified phospholipids using phosphatidylhydroxyalkanols as intermediates | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1996-05-14 | — | — | US | disclosed |
| US-5441876-A | Process for the preparation of headgroup-modified phospholipids using phosphatidylhydroxyalkanols as intermediates | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1995-08-15 | — | — | US | disclosed |
| US-5004566-A | Process for fabrication of lipid microstructures from dry organic solvent | GEO-CENTERS, INC. (US) | 1991-04-02 | — | — | US | disclosed |
| US-4990291-A | Method of making lipid tubules by a cooling process | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1991-02-05 | — | — | US | disclosed |
| US-4877501-A | Process for fabrication of lipid microstructures | SCIENCE APPLICATIONS INTERNATIONAL CORPORATION | 1989-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11344498-B2 | Compositions and methods for on-demand high-efficiency triggerable anesthesia | CACNB1, CACNA1S, CACNA1D | LMNA 236/4885ESR1 1392/4885ADORA3 224/4885 |
| US-20190070115-A1 | Compositions and Methods for On-Demand High-Efficiency Triggerable Anesthesia | CACNB1, CACNA1S, CACNA1D | LMNA 236/4885ESR1 1392/4885ADORA3 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.