SCHEMBL8960392

SCHEMBL8960392

CCOP(=O)(O)CON1C(=O)c2ccccc2C1=O

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
ALDH1A1 P00352 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2081294 0.76 GAA (0.62) GAAALDH1A1CYP1A2CYP2C9
SCHEMBL14439985 0.76 GAA (0.54) GAAALDH1A1CYP1A2CYP2C9
SCHEMBL9417135 0.75 GAA (0.62) GAAALDH1A1CYP1A2
Water SCHEMBL8678453 0.75 GAA (0.60) GAAALDH1A1CYP1A2CYP2C9
Water SCHEMBL8678452 0.75 GAA (0.60) GAAALDH1A1CYP1A2CYP2C9
SCHEMBL21749579 0.74 GAA (0.51) GAAALDH1A1CYP1A2CYP2C9
SCHEMBL9684315 0.74 GAA (0.51) GAAALDH1A1
SCHEMBL9858209 0.73 GAA (0.51) GAAALDH1A1
SCHEMBL9683399 0.72 GAA (0.50) GAAALDH1A1
SCHEMBL10439345 0.71 RECQL (0.52) GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693496-A1 Novel cephalosporins having a substituted benzyloxyimino radical in position 7, process for their preparation and their use as medicaments ROUSSEL UCLAF (FR) 1996-01-24 EP disclosed