Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 2/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 2/20 | 0.45 |
| ▸ | DDO | Q99489 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CCKAR | P32238 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31561597 | 0.86 | CA2 (0.62) | CA2AKR1B1FLT3DAOCA12 | |
| SCHEMBL3237494 | 0.86 | CA2 (0.62) | CA2AKR1B1FLT3DAOCA12 | |
| SCHEMBL30684143 | 0.84 | CA2 (0.56) | CA2AKR1B1PDGFRBPDGFRACA12 | |
| SCHEMBL4862702 | 0.84 | CA2 (0.56) | CA2AKR1B1CA12CA1CA9 | |
| SCHEMBL670176 | 0.84 | CA2 (0.56) | CA2AKR1B1PDGFRBPDGFRACA12 | |
| SCHEMBL28568569 | 0.82 | CA2 (0.71) | CA2AKR1B1FLT3DAODDO | |
| SCHEMBL29520525 | 0.82 | CA2 (0.57) | CA2AKR1B1CA12CA1CA9 | |
| SCHEMBL13542579 | 0.80 | CA2 (0.51) | CA2AKR1B1CA12CA1CA9 | |
| SCHEMBL1975132 | 0.79 | CA2 (0.50) | CA2AKR1B1DAODDOCA12 | |
| SCHEMBL14502491 | 0.78 | CA2 (0.53) | CA2AKR1B1CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567827-A | 4-Hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives | ELF SANOFI (FR) | 1996-10-22 | — | — | US | disclosed |
| US-5508431-A | 4-hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives | ELF SANOFI (FR) | 1996-04-16 | — | — | US | disclosed |
| US-5401855-A | 4-hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives | ELF SANOFI (FR) | 1995-03-28 | — | — | US | disclosed |