Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 5/20 | 0.49 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31561597 | 1.00 | CA2 (0.62) | CA2AKR1B1HTR6CNR1BCAT1 | |
| SCHEMBL28568569 | 0.88 | CA2 (0.71) | CA2AKR1B1CNR1KDM4EHSD17B10 | |
| Isoquinoline SCHEMBL27714913 | 0.87 | CA2 (0.49) | CA2AKR1B1HTR6CNR1BCAT1 | |
| SCHEMBL4862702 | 0.86 | CA2 (0.56) | CA2AKR1B1HTR6CNR1MAPT | |
| SCHEMBL670176 | 0.86 | CA2 (0.56) | CA2AKR1B1CNR1KDM4EHSD17B10 | |
| SCHEMBL8960439 | 0.86 | CA2 (0.56) | CA2AKR1B1CNR1BCAT1KDM4E | |
| SCHEMBL30684143 | 0.86 | CA2 (0.56) | CA2AKR1B1CNR1KDM4EHSD17B10 | |
| Quinoline SCHEMBL28873764 | 0.85 | CA2 (0.48) | CA2AKR1B1HTR6CNR1BCAT1 | |
| SCHEMBL29520525 | 0.84 | CA2 (0.57) | CA2AKR1B1CNR1CA12CA1 | |
| SCHEMBL4629441 | 0.84 | CA2 (0.57) | CA2AKR1B1HTR6CNR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891461-B | Synthesis method of SERD intermediate | 罗欣药业(上海)有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-119930705-A | Benzenesulfonyl indole structure modified ruthenium polypyridine complex capable of inhibiting bacterial toxins, and preparation method and application thereof | 江西科技师范大学 | 2025-05-06 | — | — | CN | claimed |
| CN-116265438-B | Synthesis method of 5-HT6 receptor molecule based on C-N-axis indole olefin axial chirality | 南京理工大学 | 2024-10-29 | — | — | CN | claimed |
| CN-116891461-A | Synthesis method of SERD intermediate | 罗欣药业(上海)有限公司 | 2023-10-17 | — | — | CN | claimed |
| CN-116265438-A | Synthesis method of 5-HT6 receptor molecule based on C-N-axis indole olefin axial chirality | 南京理工大学 | 2023-06-20 | — | — | CN | claimed |
| CN-108530339-B | Synthetic method of benzenesulfonyl-containing indole compound | 青岛农业大学 | 2020-06-05 | — | — | CN | claimed |
| CN-106366032-B | Application of the chiral organic base in water phase and an oil phase system chirality sulfur-bearing benzazolyl compounds | 中国科学院大连化学物理研究所 | 2019-04-30 | — | — | CN | claimed |
| CN-108530339-A | A kind of synthetic method of the compound of class containing Benzenesulfonylindole | 青岛农业大学 | 2018-09-14 | — | — | CN | claimed |
| CN-107522650-A | N Benzenesulfonylindole contracting amino guanidine antimicrobial compounds and preparation method thereof | 井冈山大学 | 2017-12-29 | — | — | CN | claimed |
| CN-106366032-A | Applications of chiral organic alkali in preparation of chiral sulfur-containing indole compound in water-oil two-phase system | 中国科学院大连化学物理研究所 | 2017-02-01 | — | — | CN | claimed |
| CN-101258144-A | Aminoaryl sulphonamide derivatives as functional 5-ht6 ligands | SUVEN LIFE SCIENCES LTD (IN) | 2008-09-03 | — | — | CN | claimed |
| JP-4273857-A | — | — | None | — | — | JP | disclosed |
| CN-116891461-B | Synthesis method of SERD intermediate | 罗欣药业(上海)有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-119930705-B | Benzenesulfonyl indole structure modified ruthenium polypyridine complex capable of inhibiting bacterial toxins, and preparation method and application thereof | 江西科技师范大学 | 2026-02-10 | — | — | CN | disclosed |
| CN-119930705-A | Benzenesulfonyl indole structure modified ruthenium polypyridine complex capable of inhibiting bacterial toxins, and preparation method and application thereof | 江西科技师范大学 | 2025-05-06 | — | — | CN | disclosed |
| US-4758668-A | 3-(piperidinyl)- and 3-(pyrrolidinyl)-1H-indazoles | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-07-19 | — | — | US | disclosed |
| US-4710573-A | PSYCHOLOGICAL DISORDERS | HOECHST ROUSSEL PHARMACEUTICALS, INC. (US) | 1987-12-01 | — | — | US | disclosed |
| US-4670447-A | ANALGESICS, ANTIDEPRESSANTS, ANTICONVULSANTS AND HYPOTENSIVE AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0135781-A1 | 3-(Piperidinyl)- and 3-(pyrrolidinyl)-1H-indazoles, a process for their preparation and their use as a medicament | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-04-03 | — | — | EP | disclosed |
| US-4404277-A | CYANINE DYES, SILVER HALIDE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-09-13 | — | — | US | disclosed |