Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | DUT | P33316 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213442 | 0.85 | TOP2A (0.33) | MAPTHPGDFKBP1ATOP2A | |
| SCHEMBL213441 | 0.85 | TOP2A (0.33) | MAPTHPGDFKBP1ATOP2A | |
| SCHEMBL8960409 | 0.78 | RIPK1 (0.30) | — | |
| SCHEMBL8960473 | 0.76 | HSD17B10 (0.38) | TOP2A | |
| SCHEMBL21552668 | 0.73 | TOP2A (0.32) | MAPTHPGDFKBP1ATOP2A | |
| SCHEMBL28537054 | 0.73 | TOP2A (0.32) | MAPTHPGDFKBP1ATOP2A | |
| SCHEMBL8960114 | 0.73 | LMNA (0.37) | — | |
| SCHEMBL28526409 | 0.71 | TOP2A (0.32) | FKBP1ATOP2A | |
| SCHEMBL28526405 | 0.71 | TOP2A (0.32) | FKBP1ATOP2A | |
| SCHEMBL8960475 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693058-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994024104-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1994-10-27 | — | — | WO | disclosed |