Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | BID | P55957 | 3/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.34 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960950 | 0.92 | PRKCI (0.37) | ELANECTSGTSHRGAAEP300 | |
| SCHEMBL8558518 | 0.81 | ELANE (0.48) | TYRELANECTSGMAPTMEN1 | |
| SCHEMBL8553469 | 0.77 | ELANE (0.49) | ELANECTSGMAPTMEN1HTT | |
| SCHEMBL8559099 | 0.67 | TYR (0.44) | TYRELANECTSGTSHRMAPT | |
| SCHEMBL8557956 | 0.66 | TYR (0.47) | TYRELANECTSGTSHRMAPT | |
| SCHEMBL8557438 | 0.63 | PDK2 (0.42) | TYRELANECTSGTSHRMAPT | |
| SCHEMBL9419270 | 0.60 | TYR (0.58) | TYRTSHRMAPTALOX15MEN1 | |
| SCHEMBL10327251 | 0.59 | ELANE (0.59) | TYRELANECTSGTSHRMAPT | |
| Formaldehyde SCHEMBL7994215 | 0.59 | TYR (0.60) | TYRELANECTSGTSHRMAPT | |
| Formaldehyde SCHEMBL3695076 | 0.59 | TYR (0.51) | TYRELANECTSGTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510366-A | INOTROPIC, ANTIARRHYMTHMIA AGENTS, VASODILATORS | KOWA CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |