Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 9/20 | 0.62 |
| ▸ | RXRA | P19793 | 9/20 | 0.60 |
| ▸ | RARB | P10826 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.53 |
| ▸ | RXRG | P48443 | 2/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | BAD | Q92934 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498034 | 0.92 | RXRB (0.70) | RXRBRXRARARBMCL1KDM4E | |
| SCHEMBL29771992 | 0.92 | RXRB (0.70) | RXRBRXRARARBMCL1KDM4E | |
| SCHEMBL17208853 | 0.90 | RXRB (0.60) | RXRBRXRARARBMCL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4365452 | 0.90 | RXRB (0.68) | RXRBRXRARARBMCL1KDM4E | |
| Hydrochloric Acid SCHEMBL9150803 | 0.90 | RXRB (0.68) | RXRBRXRARARBMCL1KDM4E | |
| SCHEMBL7754859 | 0.89 | RXRB (0.56) | RXRBRXRARARBRXRGBCL2L1 | |
| SCHEMBL122517 | 0.88 | ACMSD (0.63) | RXRBRXRARARBMCL1SMN1; SMN2 | |
| SCHEMBL29926573 | 0.88 | ACMSD (0.63) | RXRBRXRARARBMCL1SMN1; SMN2 | |
| SCHEMBL13522888 | 0.88 | ACMSD (0.63) | RXRBRXRARARBMCL1SMN1; SMN2 | |
| SCHEMBL8840571 | 0.88 | MCL1 (0.65) | RXRBRXRARARBMCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539243-B1 | Process for introducing a carboxyl group to an aromatic carboxylic acid or a derivative thereof | HIRAI HIDEFUMI (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5319134-A | Process for introducing a carboxyl group to an aromatic carboxylic acid or a derivative thereof | HIDEFUMI HIRAI (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0539243-A2 | Process for introducing a carboxyl group to an aromatic carboxylic acid or a derivative thereof | Hirai, Hidefumi (JP) | 1993-04-28 | — | — | EP | disclosed |