SCHEMBL1498034

SCHEMBL1498034

Cc1cc(-c2ccc(C(=O)O)c(C)c2)ccc1C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRB P28702 3/20 0.70
RXRA P19793 2/20 0.68
MCL1 Q07820 4/20 0.60
RARB P10826 4/20 0.60
KDM4E B2RXH2 1/20 0.50
GFER P55789 1/20 0.50
KMT2A Q03164 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
HNF4A P41235 1/20 0.50
ACMSD Q8TDX5 1/20 0.50
LDHA P00338 1/20 0.47
CFD P00746 1/20 0.47
PDE4A P27815 1/20 0.47
PDE4B Q07343 1/20 0.47
PDE4C Q08493 1/20 0.47
PDE4D Q08499 1/20 0.47
RARA P10276 3/20 0.47
RARG P13631 3/20 0.47
MKNK1 Q9BUB5 1/20 0.46
MKNK2 Q9HBH9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29771992 1.00 RXRB (0.70) RXRBRXRAMCL1RARBKDM4E
Hydrochloric Acid SCHEMBL9150803 0.98 RXRB (0.68) RXRBRXRAMCL1RARBKDM4E
Hydrochloric Acid SCHEMBL4365452 0.98 RXRB (0.68) RXRBRXRAMCL1RARBKDM4E
SCHEMBL17177748 0.96 RXRB (0.71) RXRBRXRAMCL1RARBKDM4E
SCHEMBL8960674 0.92 RXRB (0.62) RXRBRXRAMCL1RARBKDM4E
SCHEMBL8840571 0.92 MCL1 (0.65) RXRBRXRAMCL1RARBHNF4A
SCHEMBL29926573 0.92 ACMSD (0.63) RXRBRXRAMCL1RARBHNF4A
SCHEMBL9154339 0.92 MCL1 (0.62) RXRBRXRAMCL1RARBKDM4E
SCHEMBL13522888 0.92 ACMSD (0.63) RXRBRXRAMCL1RARBHNF4A
SCHEMBL122517 0.92 ACMSD (0.63) RXRBRXRAMCL1RARBHNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843987-A Stable zirconium-based metal organic framework material and preparation method and application thereof 浙江工业大学 2024-04-09 CN claimed
JP-4008723-A None JP disclosed
JP-6041284-A None JP disclosed
JP-7207005-A None JP disclosed
JP-6220188-A None JP disclosed
JP-3174439-A None JP disclosed
JP-6157755-A None JP disclosed
JP-5039348-A None JP disclosed
JP-4081425-A None JP disclosed
JP-4080232-A None JP disclosed
JP-H0480232-A POLYAMIDE RESIN UBE IND LTD 1992-03-13 JP disclosed
JP-H048723-A AROMATIC COPOLYESTER UBE IND LTD 1992-01-13 JP disclosed
US-5075406-A Solution polymerization of polyamides in solvent purified by adsorption on magnesia, alumina, silica or mixed oxides MITSUI TOATSU CHEMICALS, INC. (JP) 1991-12-24 US disclosed
EP-0439616-A1 METHOD OF PRODUCING 3,4,3',4'-SUBSTITUTED BIPHENYL COMPOUNDS UBE INDUSTRIES, LTD. (JP) 1991-08-07 EP disclosed
JP-H03174439-A AROMATIC COPOLYESTER UBE IND LTD 1991-07-29 JP disclosed
US-5011936-A Using composite salt consisting of at least two of silica, magnesia and alumina MITSUI TOATSU CHEMICALS, INC. (JP) 1991-04-30 US disclosed
EP-0417651-A2 Thermotropic aromatic polyester UBE INDUSTRIES, LTD. (JP) 1991-03-20 EP disclosed
US-4923951-A DIISOCYANTE, ALKALI OR ALKALINE EARTH METAL CATALYST MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-05-08 US disclosed
EP-0332425-A1 Process for refining 1,3-dimethyl-2-imidazolidinone and a process for preparing an aromatic polyamide by use of the refined product MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-09-13 EP disclosed
EP-0328342-A2 Process for producing aromatic polyamides MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-16 EP disclosed