SCHEMBL8960711

SCHEMBL8960711

CC1(C)CC(Nc2nc3ccccc3nc2NC2CC(C)(C)NC(C)(C)C2)CC(C)(C)N1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
KMT2A Q03164 3/20 0.54
LMNA P02545 2/20 0.54
MEN1 O00255 1/20 0.54
MAPT P10636 1/20 0.54
PKM P14618 1/20 0.54
ALOX15 P16050 1/20 0.54
ALOX12 P18054 1/20 0.54
RAD52 P43351 1/20 0.54
GFER P55789 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
KCNH2 Q12809 2/20 0.47
KDM1A O60341 1/20 0.45
POLB P06746 1/20 0.42
KDM4E B2RXH2 3/20 0.42
GAA P10253 1/20 0.42
EZH2 Q15910 3/20 0.41
TSHR P16473 2/20 0.41
HTT P42858 1/20 0.40
PIM1 P11309 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8960862 0.81 WHR1 (0.54) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL8960634 0.80 KDM4E (0.54) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL3604835 0.76 KMT2A (0.49) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL15147259 0.76 KCNH2 (0.53) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL9380274 0.75 KMT2A (0.87) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL15607406 0.72 KCNH2 (0.60) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL10780921 0.72 ALDH1A1 (0.77) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL3079982 0.72 ALDH1A1 (0.47) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL3606002 0.72 ALDH1A1 (0.46) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL21895103 0.72 KMT2A (0.52) ALDH1A1KMT2ALMNAMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5571899-A DYEING PLASTICS, LACQUERS, INKS, LIGHTFASTNESS, WEATHER RESISTANCE SANDOZ, LTD. (CH) 1996-11-05 US claimed
US-5510467-A EXCELLENT AS PIGMENTS, USEFUL FOR DYEING SOLVENT-FREE OR SOLVENT CONTAINING PLASTICS SANDOZ LTD. (CH) 1996-04-23 US claimed