Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.87 |
| ▸ | LMNA | P02545 | 2/20 | 0.87 |
| ▸ | MEN1 | O00255 | 1/20 | 0.87 |
| ▸ | MAPT | P10636 | 1/20 | 0.87 |
| ▸ | PKM | P14618 | 1/20 | 0.87 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.87 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.87 |
| ▸ | RAD52 | P43351 | 1/20 | 0.87 |
| ▸ | GFER | P55789 | 1/20 | 0.87 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.87 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8738952 | 0.93 | ALDH1A1 (1.00) | KMT2AALDH1A1LMNAMEN1MAPT | |
| SCHEMBL10780921 | 0.90 | ALDH1A1 (0.77) | KMT2AALDH1A1LMNAMEN1MAPT | |
| SCHEMBL9372093 | 0.81 | KMT2A (0.61) | KMT2AALDH1A1LMNAMEN1MAPT | |
| SCHEMBL20357747 | 0.81 | ALDH1A1 (0.66) | KMT2AALDH1A1LMNAMEN1MAPT | |
| SCHEMBL7793247 | 0.80 | KMT2A (0.59) | KMT2AALDH1A1LMNAMEN1MAPT | |
| SCHEMBL3601057 | 0.80 | ALDH1A1 (0.59) | KMT2AALDH1A1LMNAMEN1MAPT | |
| SCHEMBL19780825 | 0.79 | ALDH1A1 (0.77) | KMT2AALDH1A1LMNAMEN1MAPT | |
| SCHEMBL28464888 | 0.78 | ALDH1A1 (0.60) | KMT2AALDH1A1LMNAMEN1MAPT | |
| SCHEMBL19782763 | 0.78 | ALDH1A1 (0.74) | KMT2AALDH1A1LMNAMEN1MAPT | |
| SCHEMBL2289255 | 0.77 | GAA (0.62) | KMT2AALDH1A1LMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355645-B1 | Cyclic amidines and process for their preparation | BAYER AG (DE) | 1994-04-27 | — | — | EP | disclosed |
| EP-0355645-A2 | Cyclic amidines and process for their preparation | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |