Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | ERN1 | O75460 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770512 | 0.91 | ALDH1A1 (0.67) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL15329890 | 0.90 | ALDH1A1 (0.54) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL29788086 | 0.88 | CHEK1 (0.60) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL504872 | 0.88 | CHEK1 (0.60) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL17177740 | 0.87 | ALDH1A1 (0.62) | ALDH1A1CHEK1KDM4EAPAF1RECQL | |
| SCHEMBL1921738 | 0.86 | ALDH1A1 (0.57) | ALDH1A1CHEK1KDM4EAPAF1RECQL | |
| SCHEMBL10459347 | 0.86 | ALDH1A1 (0.61) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL2040708 | 0.86 | CA12 (0.72) | PDE4APDE4BPDE4CPDE4DRXRA | |
| SCHEMBL966378 | 0.85 | CA12 (0.71) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL1921213 | 0.85 | ALDH1A1 (0.56) | ALDH1A1ERN1CHEK1KDM4EAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556486-B | Rare earth organic framework material for iron ion fluorescence detection and preparation method thereof | 中国计量大学 | 2020-08-18 | — | — | CN | disclosed |
| EP-0539243-B1 | Process for introducing a carboxyl group to an aromatic carboxylic acid or a derivative thereof | HIRAI HIDEFUMI (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5319134-A | Process for introducing a carboxyl group to an aromatic carboxylic acid or a derivative thereof | HIDEFUMI HIRAI (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0539243-A2 | Process for introducing a carboxyl group to an aromatic carboxylic acid or a derivative thereof | Hirai, Hidefumi (JP) | 1993-04-28 | — | — | EP | disclosed |