Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770512 | 0.94 | ALDH1A1 (0.67) | ALDH1A1KDM4ENPC1MAPK1RAB9A | |
| SCHEMBL17177740 | 0.91 | ALDH1A1 (0.62) | ALDH1A1KDM4ENPC1MAPK1RAB9A | |
| SCHEMBL4600656 | 0.89 | CFD (0.61) | ALDH1A1KDM4ENPC1MAPK1RAB9A | |
| SCHEMBL29788086 | 0.87 | CHEK1 (0.60) | ALDH1A1KDM4EAPAF1RECQLCASP6 | |
| SCHEMBL504872 | 0.87 | CHEK1 (0.60) | ALDH1A1KDM4EAPAF1RECQLCASP6 | |
| SCHEMBL8960746 | 0.86 | PDE4A (0.57) | ALDH1A1KDM4EAPAF1RECQLCASP6 | |
| SCHEMBL1921738 | 0.86 | ALDH1A1 (0.57) | ALDH1A1KDM4ENPC1MAPK1RAB9A | |
| SCHEMBL1921213 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3133634 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28008505 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KDM4ENPC1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916145-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | HOFFMANN-LA ROCHE INC. (US) | 1990-04-10 | — | — | US | disclosed |