Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658696 | 0.83 | GAA (0.39) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL7627786 | 0.83 | MEN1 (0.39) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL30667161 | 0.83 | MEN1 (0.39) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL30457518 | 0.81 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL8380602 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL625779 | 0.81 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL1806437 | 0.80 | MPL (0.38) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL31303476 | 0.79 | MEN1 (0.40) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL10647911 | 0.79 | POLB (0.37) | ALDH1A1MEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL10648574 | 0.79 | KMT2A (0.36) | ALDH1A1MEN1KMT2APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388778-B1 | Preparation of dioxolane derivatives | HOFFMANN LA ROCHE (CH) | 1996-01-10 | — | — | EP | disclosed |
| EP-0388778-A2 | Preparation of dioxolane derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-09-26 | — | — | EP | disclosed |