Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA4 | P22748 | 2/20 | 0.62 |
| ▸ | CA6 | P23280 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.62 |
| ▸ | TPMT | P51580 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27619794 | 0.85 | CA12 (0.50) | CA12CA1CA2CA4CA6 | |
| SCHEMBL28857298 | 0.83 | CA1 (0.69) | CA12CA1CA2CA4CA6 | |
| SCHEMBL18031421 | 0.83 | CA12 (0.47) | CA12CA1CA2CA4CA6 | |
| SCHEMBL18288064 | 0.83 | ALOX15 (0.55) | CA12CA1CA2CA4CA6 | |
| SCHEMBL2671487 | 0.81 | KDM4E (0.62) | CA12CA1CA2CA4CA6 | |
| SCHEMBL4946900 | 0.80 | KDM4E (0.70) | CA12CA1CA2CA4CA6 | |
| SCHEMBL7572866 | 0.80 | TPMT (0.59) | CA12CA1CA2CA4CA6 | |
| SCHEMBL2908864 | 0.80 | TPMT (0.54) | CA12CA1CA2CA4CA6 | |
| SCHEMBL8164689 | 0.79 | CA12 (0.57) | CA12CA1CA2CA4CA6 | |
| SCHEMBL38656246 | 0.79 | CA12 (0.57) | CA12CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539243-B1 | Process for introducing a carboxyl group to an aromatic carboxylic acid or a derivative thereof | HIRAI HIDEFUMI (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5319134-A | Process for introducing a carboxyl group to an aromatic carboxylic acid or a derivative thereof | HIDEFUMI HIRAI (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0539243-A2 | Process for introducing a carboxyl group to an aromatic carboxylic acid or a derivative thereof | Hirai, Hidefumi (JP) | 1993-04-28 | — | — | EP | disclosed |