Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.69 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961076 | 0.88 | MTNR1A (0.57) | MTNR1AMTNR1BMEN1LMNACYP1A2 | |
| SCHEMBL8961269 | 0.85 | MTNR1A (0.57) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8961055 | 0.84 | MTNR1A (0.73) | MTNR1AMTNR1BMEN1LMNACYP1A2 | |
| SCHEMBL8961054 | 0.84 | MTNR1A (0.71) | MTNR1AMTNR1BMEN1LMNACYP1A2 | |
| SCHEMBL8960838 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8610577 | 0.82 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL8960949 | 0.81 | MTNR1A (0.56) | MTNR1AMTNR1BMEN1LMNACYP1A2 | |
| SCHEMBL8054334 | 0.78 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL761446 | 0.77 | MTNR1A (0.73) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL29941181 | 0.77 | MTNR1A (0.73) | MTNR1AMTNR1BNQO2HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552418-A | FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1996-09-03 | — | — | US | disclosed |