Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 10/20 | 0.56 |
| ▸ | CA12 | O43570 | 9/20 | 0.56 |
| ▸ | GLA | P06280 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 2/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19691118 | 0.87 | CA12 (0.58) | KDM4EGAAALDH1A1POLBL3MBTL1 | |
| SCHEMBL1099580 | 0.83 | CA9 (0.58) | KDM4EGAAALDH1A1POLBCA9 | |
| SCHEMBL7519267 | 0.81 | CA9 (0.58) | KDM4EGAAALDH1A1POLBCA9 | |
| Umbelliferone SCHEMBL17063687 | 0.79 | CA12 (0.68) | KDM4EGAAALDH1A1POLBL3MBTL1 | |
| SCHEMBL15842832 | 0.79 | KDM4E (0.56) | KDM4EGAAALDH1A1POLBL3MBTL1 | |
| SCHEMBL15689131 | 0.77 | CA9 (0.51) | KDM4EGAAALDH1A1POLBCA9 | |
| SCHEMBL15842560 | 0.77 | GBA1 (0.61) | KDM4EGAAALDH1A1POLBCA9 | |
| SCHEMBL15842612 | 0.77 | PTPN1 (0.53) | KDM4EGAAALDH1A1POLBL3MBTL1 | |
| Coumarin SCHEMBL14744008 | 0.77 | CA12 (0.67) | KDM4EGAAALDH1A1POLBL3MBTL1 | |
| SCHEMBL28373618 | 0.77 | CA12 (0.60) | KDM4EGAAALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693064-A1 | HYDROPHOBIC AMINOCOUMARIN DERIVATIVES AND THEIR USE AS PROTEOLYTIC ENZYME SUBSTRATES OR IN THE PREPARATION OF SUCH SUBSTRATES | Seratec (FR) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994024118-A1 | HYDROPHOBIC AMINOCOUMARIN DERIVATIVES AND THEIR USE AS PROTEOLYTIC ENZYME SUBSTRATES OR IN THE PREPARATION OF SUCH SUBSTRATES | SERATEC (FR) | 1994-10-27 | — | — | WO | disclosed |