SCHEMBL1099580

SCHEMBL1099580

O=C(O)c1ccc2ccc(=O)oc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 11/20 0.58
CA12 O43570 10/20 0.58
KDM4E B2RXH2 8/20 0.58
ALDH1A1 P00352 6/20 0.58
CA1 P00915 5/20 0.58
HPGD P15428 4/20 0.58
KMT2A Q03164 3/20 0.58
GLA P06280 3/20 0.58
GAA P10253 3/20 0.58
AKR1B1 P15121 3/20 0.58
HSD17B10 Q99714 3/20 0.58
MCL1 Q07820 3/20 0.58
TDP1 Q9NUW8 3/20 0.58
CASP1 P29466 2/20 0.58
CASP7 P55210 2/20 0.58
ERAP1 Q9NZ08 2/20 0.58
MEN1 O00255 1/20 0.58
POLB P06746 3/20 0.54
LMNA P02545 2/20 0.53
MAPT P10636 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1100153 0.87 CA12 (0.59) CA9CA12KDM4EALDH1A1CA1
SCHEMBL30388813 0.87 CA12 (0.59) CA9CA12KDM4EALDH1A1CA1
Hydrochloric Acid SCHEMBL23294784 0.85 CA12 (0.58) CA9CA12KDM4EALDH1A1CA1
SCHEMBL7519267 0.83 CA9 (0.58) CA9CA12KDM4EALDH1A1CA1
SCHEMBL8960975 0.83 KDM4E (0.56) CA9CA12KDM4EALDH1A1CA1
SCHEMBL28780650 0.82 CA9 (0.51) CA9CA12KDM4EALDH1A1CA1
SCHEMBL28373618 0.82 CA12 (0.60) CA9CA12KDM4EALDH1A1CA1
SCHEMBL15842832 0.80 KDM4E (0.56) CA9CA12KDM4EALDH1A1CA1
Umbelliferone SCHEMBL21043923 0.80 CA12 (0.72) CA9CA12KDM4EALDH1A1CA1
SCHEMBL12679315 0.80 CA12 (0.64) CA9CA12KDM4EALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
CN-100488504-C Coumarin amide derivative, its preparation method, its medicinal composition and application INST MATERIA MEDICA CAMS (CN) 2009-05-20 CN claimed
CN-121575589-A Crease-resistant ultraviolet-resistant core twine yarn and preparation method thereof 徐州时代纺织有限公司 2026-02-27 CN disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US disclosed
CN-104178516-A Saccharumsinense fermented extract and preparation method and application thereof CHINA TOBACCO YUNNAN IND CO LTD 2014-12-03 CN disclosed
EP-1988085-B1 PROCESS FOR PRODUCTION OF 3-[5-[4-(CYCLOPENTYLOXY)-2-HYDROXYBENZOYL]-2-[(3-HYDROXY-1,2-BEZISOXAZOL-6-YL)METHOXY]PHENYL]PROPIONATE ESTER AND INTERMEDIATE FOR THE PROCESS TOYAMA CHEMICAL CO LTD (JP) 2014-11-12 EP disclosed
EP-2562170-B1 Process for production of 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-oxo-2-substituted-2,3-dihydro-1,2-benzisoxazol-6-yl)methoxy]phenyl]propionate ester and intermediate for the process TOYAMA CHEMICAL CO LTD (JP) 2014-10-29 EP disclosed
EP-2562170-B1 Process for production of 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-oxo-2-substituted-2,3-dihydro-1,2-benzisoxazol-6-yl)methoxy]phenyl]propionate ester and intermediate for the process TOYAMA CHEMICAL CO LTD (JP) 2014-10-29 EP disclosed
CN-102285931-B Process for production of 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-hydroxy-1,2-bezisoxazol-6-yl)methoxy]phenyl]propionate ester and intermediate for the process TOYAMA CHEMICAL CO LTD 2014-01-01 CN disclosed
EP-2562170-A1 Process for production of 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-oxo-2-substituted-2,3-dihydro-1,2-benzisoxazol-6-yl)methoxy]phenyl]propionate ester and intermediate for the process TOYAMA CHEMICAL CO., LTD. (JP) 2013-02-27 EP disclosed
WO-2009006184-A1 DISCODERMOLIDE ANALOGUES AND METHODS OF THEIR USE THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2009-01-08 WO disclosed
US-20090002802-A1 ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE RICOH COMPANY, LTD. (JP) 2009-01-01 US disclosed
EP-1988085-A1 PROCESS FOR PRODUCTION OF 3-[5-[4-(CYCLOPENTYLOXY)-2-HYDROXYBENZOYL]-2-[(3-HYDROXY-1,2-BEZISOXAZOL-6-YL)METHOXY]PHENYL]PROPIONATE ESTER AND INTERMEDIATE FOR THE PROCESS TOYAMA CHEMICAL CO., LTD. (JP) 2008-11-05 EP disclosed
US-6306587-B1 APPARATUS OF VESSEL FOR RECEIVING SAMPLE AND TWO PROBES, EACH HAVING FUNCTIONAL GROUPS CAPABLE OF REACTING WITH EACH OTHER TO FORM COVALENT BOND; LIGHT SOURCE TO ACTIVATE GROUPS; AND DETECTOR TO DETECT REACTION PRODUCT VYSIS, INC. 2001-10-23 US disclosed
US-5686243-A DETECTING POLYNUCLEOTIDE SEQUENCES; HYBRIDIZATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-11-11 US disclosed
US-5449602-A Polynucleotides AMOCO CORPORATION (US) 1995-09-12 US disclosed
EP-0324616-B1 Template-directed photoligation AMOCO CORP (US) 1995-03-29 EP disclosed
EP-0324616-A2 Template-directed photoligation AMOCO CORPORATION (US) 1989-07-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 CA9 120/4885CA12 15/4885KDM4E 2504/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA CA9 526/4885CA12 403/4885KDM4E 1109/4885
US-20090002802-A1 ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE EPCAM, ILK, L1CAM CA9 1250/4885CA12 480/4885KDM4E 2183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.