SCHEMBL8961158

SCHEMBL8961158

C/C=C/C(=O)NC(C)(C)CS(=O)(=O)O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.32
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10791527 1.00 KMT2A (0.32) KMT2ARAB9ASMN1; SMN2
SCHEMBL7217968 0.98 KMT2A (0.31) KMT2ARAB9ASMN1; SMN2
SCHEMBL14590410 0.84 L3MBTL1 (0.44) KMT2ARAB9ASMN1; SMN2
Crotonic Acid SCHEMBL30355324 0.82 ALDH1A1 (0.42) KMT2A
SCHEMBL9578217 0.82 POLB (0.43) KMT2A
SCHEMBL7217966 0.82 POLB (0.43) KMT2A
SCHEMBL19512082 0.82 KMT2A (0.31) KMT2ARAB9ASMN1; SMN2
Propene SCHEMBL28207817 0.80 ALDH1A1 (0.45) KMT2A
SCHEMBL28723020 0.79 ALDH1A1 (0.47) KMT2A
SCHEMBL19490 0.79 ALDH1A1 (0.47) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0558612-B1 POLYMER BLENDS FOR AQUEOUS DISPERSIONS HAVING IMPROVED FREEZE-THAW STABILITY EASTMAN CHEM CO (US) 1996-01-10 EP claimed
US-4701283-A FROM AN UNSATURATED NITRILE AND B-HYDROXYALKANESULFONIC ACID IN FUMING SULFURIC ACID MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1987-10-20 US disclosed
EP-0112921-B1 PROCESS FOR PREPARING AMIDOALKANESULFONIC ACID DERIVATIVES MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-07-15 EP disclosed
US-4659773-A COPOLYMERIZING EMULSION WITH A RADICAL POLYMERIZABLE UNSATURATED BOND MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1987-04-21 US disclosed
EP-0112921-A1 PROCESS FOR PREPARING AMIDOALKANESULFONIC ACID DERIVATIVES MITSUI TOATSU CHEMICALS, Inc. (JP) 1984-07-11 EP disclosed