SCHEMBL8961179

SCHEMBL8961179

CO[Si](C)(CCc1ccc(CN)cc1)OC

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 6/20 0.40
TAAR1 Q96RJ0 4/20 0.39
HRH3 Q9Y5N1 1/20 0.39
MAOB P27338 3/20 0.38
ABAT P80404 1/20 0.37
ST14 Q9Y5Y6 1/20 0.36
LOX P28300 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2A6 P11509 1/20 0.34
PSIP1 O75475 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL163507 0.89 TAAR1 (0.37) TAAR1MAOB
SCHEMBL8953980 0.84 GFER (0.50) LOXL2TAAR1MAOB
SCHEMBL387841 0.82 CYP1A2 (0.45) TAAR1HRH3CYP1A2CYP2A6
SCHEMBL9660429 0.82 TAAR1 (0.45) LOXL2TAAR1HRH3MAOBABAT
SCHEMBL14498249 0.82 TAAR1 (0.36) TAAR1MAOB
SCHEMBL3339284 0.80 CYP4A11 (0.32) TAAR1
SCHEMBL15735387 0.80 TAAR1 (0.44) TAAR1MAOB
SCHEMBL17656478 0.80 TAAR1 (0.53) TAAR1MAOB
SCHEMBL27832615 0.80 ESR1 (0.50) TAAR1
SCHEMBL1584725 0.79 TDP1 (0.44) LOXL2TAAR1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0618246-B1 Aqueous silylated epoxy resin dispersion OSI SPECIALTIES INC (US) 1996-01-31 EP disclosed
EP-0618246-A2 Aqueous silylated epoxy resin dispersion OSi Specialties, Inc. (US) 1994-10-05 EP disclosed