SCHEMBL8961286

SCHEMBL8961286

CCCC1CCC(CCc2ccc(F)c(F)c2)CC1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
MAOB P27338 3/20 0.39
MAOA P21397 2/20 0.39
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 2/20 0.37
HTT P42858 1/20 0.37
CNR1 P21554 1/20 0.36
RIPK1 Q13546 1/20 0.36
DAO P14920 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8146444 1.00 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL10479865 0.98 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL10479867 0.98 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL9809556 0.97 MAOB (0.40) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL4798556 0.95 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL4798573 0.95 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL8771449 0.95 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL4798580 0.95 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL12031951 0.94 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL9331622 0.91 SLC6A2 (0.37) SLC6A2SLC6A4SLC6A3MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0502407-B1 Nematic liquid-crystal composition for active matrix application SHARP KK (JP) 1996-02-07 EP claimed
JP-2111734-A None JP disclosed
CN-103805208-B Dicyclohexyl ethylene group substituted diphenylamine alkynes liquid crystalline cpd and preparation method thereof SHAANXI NORMAL UNIVERSITY (CN) 2015-08-19 CN disclosed
EP-0502407-B1 Nematic liquid-crystal composition for active matrix application SHARP KK (JP) 1996-02-07 EP disclosed
US-5330679-A Low temperature stability MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-07-19 US disclosed
EP-0502407-A1 Nematic liquid-crystal composition for active matrix application SHARP CORPORATION (JP) 1992-09-09 EP disclosed
JP-H02111734-A CYCLOHEXANE DERIVATIVE CHISSO CORP 1990-04-24 JP disclosed
US-4917819-A Cyclohexane derivative and liquid crystal composition containing same CHISSO CORPORATION (JP) 1990-04-17 US disclosed
EP-0205998-B1 CYCLOHEXANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME Chisso Corporation (JP) 1990-02-28 EP disclosed
US-4797228-A Cyclohexane derivative and liquid crystal composition containing same CHISSO CORPORATION (JP) 1989-01-10 US disclosed
EP-0205998-A1 Cyclohexane derivative and liquid crystal composition containing same Chisso Corporation (JP) 1986-12-30 EP disclosed