SCHEMBL4798573

SCHEMBL4798573

CCCC1CCC(C2CCC(CCc3ccc(F)c(F)c3)CC2)CC1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
MAOB P27338 3/20 0.37
MAOA P21397 2/20 0.37
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 2/20 0.35
CNR1 P21554 1/20 0.34
HTT P42858 1/20 0.34
RIPK1 Q13546 1/20 0.34
TLR4 O00206 1/20 0.34
DAO P14920 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8771449 1.00 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL4798580 1.00 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL4798556 1.00 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL8961286 0.95 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL8146444 0.95 SLC6A2 (0.42) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL12032041 0.94 SLC6A2 (0.36) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL10479865 0.94 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL10479867 0.94 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL9809556 0.92 MAOB (0.40) SLC6A2SLC6A4SLC6A3MAOBMAOA
SCHEMBL21581480 0.92 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115981060-A High-shielding-degree electric control dimming color-changing film and preparation method thereof 珠海兴业新材料科技有限公司 2023-04-18 CN claimed
EP-0502407-B1 Nematic liquid-crystal composition for active matrix application SHARP KK (JP) 1996-02-07 EP claimed
CN-115981060-A High-shielding-degree electric control dimming color-changing film and preparation method thereof 珠海兴业新材料科技有限公司 2023-04-18 CN disclosed
US-20210102122-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2021-04-08 US disclosed
US-9493704-B2 Cycloheptane derivative and preparation method and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) 2016-11-15 US disclosed
US-9493704-B2 Cycloheptane derivative and preparation method and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) 2016-11-15 US disclosed
US-20150252261-A1 CYCLOHEPTANE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD (CN) 2015-09-10 US disclosed
US-20150252261-A1 CYCLOHEPTANE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD (CN) 2015-09-10 US disclosed
US-7951577-B2 Liquid crystals with reduced toxicity and applications thereof WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-05-31 US disclosed
US-7820251-B2 Liquid crystal compound and liquid crystal display utilizing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-10-26 US disclosed
US-7820251-B2 Liquid crystal compound and liquid crystal display utilizing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-10-26 US disclosed
WO-1991000898-A1 SUPER-TWIST LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-01-24 WO disclosed
EP-0406468-A1 Nematic-liquid-crystal composition for active matrix application SHARP CORPORATION (JP) 1991-01-09 EP disclosed
EP-0394419-A1 MATRIX LIQUID CRYSTAL DISPLAY. MERCK PATENT GMBH (DE) 1990-10-31 EP disclosed
WO-1990004623-A1 MATRIX LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-05-03 WO disclosed
EP-0365962-A1 Matrix-type liquid-crystal display MERCK PATENT GmbH (DE) 1990-05-02 EP disclosed
US-4917819-A Cyclohexane derivative and liquid crystal composition containing same CHISSO CORPORATION (JP) 1990-04-17 US disclosed
EP-0205998-B1 CYCLOHEXANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME Chisso Corporation (JP) 1990-02-28 EP disclosed
US-4797228-A Cyclohexane derivative and liquid crystal composition containing same CHISSO CORPORATION (JP) 1989-01-10 US disclosed
EP-0205998-A1 Cyclohexane derivative and liquid crystal composition containing same Chisso Corporation (JP) 1986-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150252261-A1 CYCLOHEPTANE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF DHPS, DHCR24, CCNT1 SLC6A2 4251/4885SLC6A4 3548/4885SLC6A3 3818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.