Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8146444 | 0.97 | SLC6A2 (0.42) | MAOBSLC6A2SLC6A4SLC6A3MAOA | |
| SCHEMBL8961286 | 0.97 | SLC6A2 (0.42) | MAOBSLC6A2SLC6A4SLC6A3MAOA | |
| SCHEMBL10479867 | 0.95 | SLC6A2 (0.41) | MAOBSLC6A2SLC6A4SLC6A3MAOA | |
| SCHEMBL10479865 | 0.95 | SLC6A2 (0.41) | MAOBSLC6A2SLC6A4SLC6A3MAOA | |
| SCHEMBL4798573 | 0.92 | SLC6A2 (0.40) | MAOBSLC6A2SLC6A4SLC6A3MAOA | |
| SCHEMBL4798580 | 0.92 | SLC6A2 (0.40) | MAOBSLC6A2SLC6A4SLC6A3MAOA | |
| SCHEMBL4798556 | 0.92 | SLC6A2 (0.40) | MAOBSLC6A2SLC6A4SLC6A3MAOA | |
| SCHEMBL8771449 | 0.92 | SLC6A2 (0.40) | MAOBSLC6A2SLC6A4SLC6A3MAOA | |
| SCHEMBL12031951 | 0.91 | SLC6A2 (0.40) | MAOBSLC6A2SLC6A4SLC6A3MAOA | |
| SCHEMBL9302628 | 0.88 | CYP2C9 (0.48) | ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427837-A1 | RING COMPOUNDS | MERCK PATENT GmbH (DE) | 1991-05-22 | — | — | EP | disclosed |
| WO-1990015114-A1 | RING COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-12-13 | — | — | WO | disclosed |