Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961381 | 0.83 | CYP3A4 (0.40) | HMGCRCYP3A4GAA | |
| SCHEMBL17860895 | 0.78 | HMGCR (0.34) | HMGCRMEN1KMT2ALMNALPAR3 | |
| SCHEMBL8961431 | 0.72 | HMGCR (0.36) | HMGCRMEN1KMT2ALMNALPAR3 | |
| SCHEMBL8961408 | 0.72 | LMNA (0.38) | LMNAALDH1A1 | |
| SCHEMBL10990547 | 0.72 | MEN1 (0.38) | HMGCRMEN1KMT2ALMNALPAR3 | |
| SCHEMBL4449824 | 0.72 | LPAR5 (0.39) | HMGCRMEN1KMT2ALMNALPAR3 | |
| SCHEMBL4457979 | 0.71 | LPAR5 (0.36) | HMGCRMEN1KMT2ALMNALPAR3 | |
| SCHEMBL12942609 | 0.69 | PLA2G2A (0.37) | LMNAGAAALDH1A1 | |
| SCHEMBL17878617 | 0.68 | HMGCR (0.33) | HMGCRMEN1KMT2ALMNALPAR3 | |
| SCHEMBL6307077 | 0.68 | HCAR2 (0.34) | HMGCRMEN1KMT2ALMNALPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532402-A | Process for producing optically active hydroxyalkylphosphonates | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-07-02 | — | — | US | disclosed |