SCHEMBL8961342

SCHEMBL8961342

CC(C)CC(=O)C(=O)OC(=O)C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.38
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PRKCA P17252 1/20 0.32
ELANE P08246 1/20 0.32
CYP2C19 P33261 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP9 P14780 1/20 0.31
MMP13 P45452 1/20 0.31
MMP8 P22894 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27986649 0.82 CA2 (0.48) CA2ALDH1A1TDP1CYP2C19SMN1; SMN2
SCHEMBL8736205 0.78 ELANE (0.32) ALDH1A1TDP1PRKCAELANE
SCHEMBL20725777 0.76 CA2 (0.32) CA2ALDH1A1TDP1MMP1MMP2
SCHEMBL21571489 0.76 CA2 (0.42) CA2ALDH1A1TDP1PRKCACYP2C19
SCHEMBL1088881 0.74 CA2 (0.41) CA2ALDH1A1TDP1CYP2C19MMP1
SCHEMBL392424 0.72 CES2 (0.46) ALDH1A1ELANE
SCHEMBL1089752 0.70 CA2 (0.46) CA2ALDH1A1TDP1CYP2C19MMP1
SCHEMBL7220097 0.70 CA2 (0.46) CA2ALDH1A1TDP1CYP2C19SMN1; SMN2
SCHEMBL8733360 0.69 CES1 (0.50) ALDH1A1ELANE
SCHEMBL20725789 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693473-A1 Method of producing pivaloylacetic acid ester UBE INDUSTRIES, LTD. (JP) 1996-01-24 EP disclosed