Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15820261 | 0.79 | — | — | |
| Potassium Ion SCHEMBL11306810 | 0.79 | — | — | |
| Lithium Ion SCHEMBL26631940 | 0.79 | — | — | |
| Pivalate SCHEMBL1950250 | 0.77 | CA1 (0.43) | CA1CA4ALDH1A1TSHR | |
| Pivalate SCHEMBL28706057 | 0.77 | CA1 (0.43) | CA1CA4ALDH1A1TSHR | |
| SCHEMBL5082325 | 0.76 | — | — | |
| Acetic Acid SCHEMBL11464477 | 0.76 | CA1 (0.53) | CA1CA4FDPSMEN1LDHA | |
| SCHEMBL11587159 | 0.74 | CA1 (0.40) | CA1CA4ALDH1A1TSHR | |
| SCHEMBL11048278 | 0.74 | GGT1 (0.32) | — | |
| Tert-Butylamine SCHEMBL19171185 | 0.73 | ALDH1A1 (0.42) | CA1CA4FDPSALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693081-A1 | CYCLIC COMPOUNDS AND COMPOSITIONS WHICH INHIBIT BONE RESORPTION | Novartis AG (CH) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994024153-A1 | CYCLIC COMPOUNDS AND COMPOSITIONS WHICH INHIBIT BONE RESORPTION | CIBA-GEIGY AG (CH) | 1994-10-27 | — | — | WO | disclosed |