SCHEMBL8961427

SCHEMBL8961427

Cc1cc(O)c(C(C)(C)C)c(C)c1S(=O)(=O)c1ccc(O)c(C(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
RAPGEF4 Q8WZA2 3/20 0.40
GAA P10253 2/20 0.40
PKM P14618 1/20 0.40
ALOX15 P16050 3/20 0.39
NR1I2 O75469 1/20 0.39
LMNA P02545 1/20 0.39
CYP2C9 P11712 1/20 0.39
MIF P14174 1/20 0.39
TYR P14679 1/20 0.39
HTT P42858 1/20 0.39
NFE2L2 Q16236 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
POLB P06746 2/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
TP53 P04637 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2595702 0.79 ALDH1A1 (0.55) ALDH1A1GAAPKMALOX15NR1I2
SCHEMBL10788397 0.79 ALDH1A1 (0.55) ALDH1A1GAAPKMALOX15NR1I2
SCHEMBL17298623 0.78 ALDH1A1 (0.50) ALDH1A1RAPGEF4GAAPKMALOX15
SCHEMBL10527665 0.73 ALDH1A1 (0.58) ALDH1A1RAPGEF4GAAPKMALOX15
SCHEMBL16117681 0.71 ALDH1A1 (0.57) ALDH1A1ALOX15NR1I2LMNACYP2C9
SCHEMBL12212829 0.71 ALDH1A1 (0.53) ALDH1A1ALOX15NR1I2LMNACYP2C9
SCHEMBL29588513 0.71 ALDH1A1 (0.57) ALDH1A1ALOX15NR1I2LMNACYP2C9
SCHEMBL27866996 0.70 ALDH1A1 (0.42) ALDH1A1ALOX15NR1I2LMNACYP2C9
SCHEMBL8057422 0.66 RAPGEF4 (0.65) ALDH1A1RAPGEF4GAAPKMHTT
SCHEMBL6668819 0.66 ALDH1A1 (0.54) ALDH1A1RAPGEF4GAAPKMALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0599580-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1996-02-07 EP claimed
US-5446009-A Thermal color developing layer consists of an organic color developer, a higher fatty acid metal double salt and an electron doner; storage stability, oil/plasticizing/weather/ light resistance NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1995-08-29 US claimed
EP-0599580-A1 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1994-06-01 EP claimed