Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796156 | 0.84 | CDK2 (0.43) | KCNH3 | |
| SCHEMBL8961467 | 0.80 | TAAR1 (0.56) | ADORA2AADORA1CTSKADORA2BTDP1 | |
| SCHEMBL18670793 | 0.78 | MAPT (0.50) | TDP1KCNH3 | |
| SCHEMBL9277726 | 0.77 | MAPT (0.51) | KCNH3 | |
| SCHEMBL9501348 | 0.77 | ALDH1A1 (0.44) | KCNH3 | |
| SCHEMBL8961454 | 0.75 | ADORA1 (0.46) | ADORA2AADORA1CTSKADORA2BTDP1 | |
| SCHEMBL9500192 | 0.74 | ALDH1A1 (0.42) | KCNH3 | |
| SCHEMBL4220703 | 0.70 | AURKA (0.59) | ADORA2AADORA1CTSKADORA2B | |
| SCHEMBL12483417 | 0.69 | SLC2A1 (0.46) | ADORA1ADORA2B | |
| SCHEMBL31484109 | 0.69 | MAPT (0.60) | ADORA2AADORA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457726-B1 | 2-Anilinopyrimidine derivatives as pesticides | CIBA GEIGY AG (CH) | 1996-02-07 | — | — | EP | claimed |
| EP-0457726-A1 | 2-Anilinopyrimidine derivatives as pesticides | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | claimed |
| EP-0457726-B1 | 2-Anilinopyrimidine derivatives as pesticides | CIBA GEIGY AG (CH) | 1996-02-07 | — | — | EP | disclosed |
| US-5439912-A | Plant fungicide, insecticide, pesticide | CIBA-GEIGY CORPORATION (US) | 1995-08-08 | — | — | US | disclosed |
| EP-0457726-A1 | 2-Anilinopyrimidine derivatives as pesticides | CIBA-GEIGY AG (CH) | 1991-11-21 | — | — | EP | disclosed |