SCHEMBL9501348

SCHEMBL9501348

CCc1cc(C2CC2)nc(Nc2ccccc2)n1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
KCNH3 Q9ULD8 8/20 0.42
MEN1 O00255 2/20 0.40
MAPT P10636 2/20 0.40
KMT2A Q03164 2/20 0.40
NFKB1 P19838 1/20 0.40
MAPK1 P28482 1/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
VSIR Q9H7M9 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
NEK1 Q96PY6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9499662 0.86 ALDH1A1 (0.49) ALDH1A1KCNH3MEN1MAPTKMT2A
SCHEMBL9499269 0.85 RECQL (0.45) ALDH1A1KCNH3MEN1MAPTKMT2A
SCHEMBL9501015 0.85 KCNH3 (0.41) ALDH1A1KCNH3MEN1MAPTKMT2A
SCHEMBL9499283 0.85 KCNH3 (0.41) ALDH1A1KCNH3MEN1MAPTKMT2A
SCHEMBL9502856 0.85 KCNH3 (0.46) ALDH1A1KCNH3MEN1MAPTKMT2A
SCHEMBL9500192 0.83 ALDH1A1 (0.42) ALDH1A1KCNH3MEN1MAPTKMT2A
Cyprodinil SCHEMBL29421756 0.82 TAAR1 (0.55) ALDH1A1KCNH3MEN1MAPTKMT2A
Cyprodinil SCHEMBL22669 0.82 TAAR1 (0.55) ALDH1A1KCNH3MEN1MAPTKMT2A
Cyprodinil SCHEMBL12471945 0.81 SMN1; SMN2 (0.54) ALDH1A1MEN1MAPTKMT2AMAPK1
SCHEMBL9017592 0.79 MAPT (0.50) ALDH1A1KCNH3MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1034255-C Composition for controlling and preventing harmful insects and biocides CIBA GEIGY AG (CH) 1997-03-19 CN claimed
CN-1024489-C Method for controlling harmful insects and microorganisms on plants CIBA GEIGY AG (CH) 1994-05-18 CN claimed
EP-0310550-B1 PESTICIDE CIBA-GEIGY AG (CH) 1993-05-26 EP claimed
CN-1064191-A The composition of control or prevention harmful insect or microorganism encroach CIBA GEIGY AG (CH) 1992-09-09 CN claimed
CN-1064270-A Harmful insect and method of microorganism on the controlling plant CIBA GEIGY AG (CH) 1992-09-09 CN claimed
CN-1017993-B Process for preparing anilinopyrimidine derivatives CIBA GEIGY AG (CH) 1992-08-26 CN claimed
CN-1032441-A Pesticide CIBA GEIGY AG (CH) 1989-04-19 CN claimed
EP-0310550-A1 Pesticide CIBA-GEIGY AG (CH) 1989-04-05 EP claimed
CN-1024489-C Method for controlling harmful insects and microorganisms on plants CIBA GEIGY AG (CH) 1994-05-18 CN disclosed
EP-0310550-B1 PESTICIDE CIBA-GEIGY AG (CH) 1993-05-26 EP disclosed
US-5153200-A Insecticides, microbiocides CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed
CN-1064191-A The composition of control or prevention harmful insect or microorganism encroach CIBA GEIGY AG (CH) 1992-09-09 CN disclosed
CN-1064270-A Harmful insect and method of microorganism on the controlling plant CIBA GEIGY AG (CH) 1992-09-09 CN disclosed
CN-1017993-B Process for preparing anilinopyrimidine derivatives CIBA GEIGY AG (CH) 1992-08-26 CN disclosed
US-4997941-A Insecticides for plant protection, also used as fungicides CIBA-GEIGY CORPORATION (US) 1991-03-05 US disclosed
US-4931560-A FUNGICIDES CIBA-GEIGY CORPORATION (US) 1990-06-05 US disclosed
CN-1032441-A Pesticide CIBA GEIGY AG (CH) 1989-04-19 CN disclosed
EP-0310550-A1 Pesticide CIBA-GEIGY AG (CH) 1989-04-05 EP disclosed