Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2010279 | 0.89 | ALDH1A1 (0.60) | ALDH1A1HTTKDM4EPOLBMOK | |
| SCHEMBL29769098 | 0.83 | ALDH1A1 (0.63) | ALDH1A1HTTKDM4EPOLBMOK | |
| SCHEMBL29769157 | 0.83 | RAB9A (0.70) | ALDH1A1HTTKDM4EPOLBHPGD | |
| SCHEMBL20922083 | 0.82 | HTT (0.66) | ALDH1A1HTTKDM4EPOLBHPGD | |
| SCHEMBL7800600 | 0.81 | MAPT (0.60) | ALDH1A1HTTKDM4EPOLBHPGD | |
| SCHEMBL17478627 | 0.81 | KDM4E (0.67) | ALDH1A1HTTKDM4EHPGDRAB9A | |
| SCHEMBL2848712 | 0.80 | HPGD (0.67) | ALDH1A1HTTKDM4EPOLBMOK | |
| SCHEMBL8253702 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HTTKDM4EPOLBMOK | |
| SCHEMBL429085 | 0.79 | MAPT (0.75) | ALDH1A1KDM4EPOLBMAPTRAB9A | |
| SCHEMBL6814763 | 0.77 | MAPT (0.66) | ALDH1A1HTTHPGDMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571682-A | REDUCING INTERFERENT BIAS SUCH AS HEMOGLOBIN | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1996-11-05 | — | — | US | disclosed |