Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bifendate SCHEMBL29516235 | 1.00 | TARBP2 (0.48) | TARBP2KDM4EPOLBALDH1A1HSD17B10 | |
| Bifendate SCHEMBL30788692 | 1.00 | TARBP2 (0.48) | TARBP2KDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL25688023 | 0.93 | TARBP2 (0.44) | TARBP2KDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL9330285 | 0.92 | POLB (0.51) | TARBP2KDM4EPOLBHSD17B10MEN1 | |
| Bicyclol SCHEMBL29380248 | 0.92 | TARBP2 (0.43) | TARBP2KDM4EPOLBALDH1A1HSD17B10 | |
| Bicyclol SCHEMBL9600725 | 0.92 | TARBP2 (0.43) | TARBP2KDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL23438996 | 0.89 | TARBP2 (0.41) | TARBP2KDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL9353225 | 0.89 | TARBP2 (0.49) | TARBP2KDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL21600700 | 0.88 | TARBP2 (0.41) | TARBP2KDM4EPOLBALDH1A1HSD17B10 | |
| SCHEMBL9329516 | 0.87 | TARBP2 (0.40) | TARBP2KDM4EPOLBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504221-A | Method for resolving racemic compounds | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 1996-04-02 | — | — | US | claimed |
| US-8793078-B2 | Method for predicting activation energy using atomic fingerprint descriptor or atomic descriptor | BIOINFORMATICS & MOLECULAR DESIGN RESEARCH CENTER (KR) | 2014-07-29 | — | — | US | disclosed |
| US-20120084012-A1 | METHOD FOR PREDICTING ACTIVATION ENERGY USING ATOMIC FINGERPRINT DESCRIPTOR OR ATOMIC DESCRIPTOR | BIOINFORMATICS & MOLECULAR DESIGN RESEARCH CENTER (KR) | 2012-04-05 | — | — | US | disclosed |
| US-20110213558-A1 | METHOD FOR PREDICTING ACTIVATION ENERGY USING AN ATOMIC FINGERPRINT DESCRIPTOR OR AN ATOMIC DESCRIPTOR | BIOINFORMATICS & MOLECULAR DESIGN RESEARCH CENTER (KR) | 2011-09-01 | — | — | US | disclosed |
| EP-2354987-A2 | METHOD FOR PREDICTING ACTIVATION ENERGY USING AN ATOMIC FINGERPRINT DESCRIPTOR OR AN ATOMIC DESCRIPTOR | Bioinformatics&Molecular Design Research Center (KR) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010056053-A2 | METHOD FOR PREDICTING ACTIVATION ENERGY USING AN ATOMIC FINGERPRINT DESCRIPTOR OR AN ATOMIC DESCRIPTOR | 사단법인 분자설계연구소 (KR) | 2010-05-20 | — | — | WO | disclosed |
| EP-1708695-A1 | COMPOSITIONS AND METHOD FOR TREATMENT OF STEROID/NUCLEAR RECEPTOR-MEDIATED DISEASES | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005053724-A1 | COMPOSITIONS AND METHOD FOR TREATMENT OF STEROID/NUCLEAR RECEPTOR-MEDIATED DISEASES | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2005-06-16 | — | — | WO | disclosed |
| US-5504221-A | Method for resolving racemic compounds | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 1996-04-02 | — | — | US | disclosed |
| US-5504221-A | Method for resolving racemic compounds | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 1996-04-02 | — | — | US | disclosed |
| EP-0401125-B1 | Biphenyl derivatives, process for preparing the same and intermediates therefor | TANABE SEIYAKU CO (JP) | 1994-08-24 | — | — | EP | disclosed |
| EP-0267970-B1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5264594-A | Alkylation of carbonates | TSUMURA & CO. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5233057-A | For treatment or prophylaxis of liver disorders | TANABE SEIYAKU CO., LTD. (JP) | 1993-08-03 | — | — | US | disclosed |
| US-5182404-A | Liver disorders | TANABE SEIYAKE CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |
| US-5103023-A | Carboxy derivates with oxy subsitituents for treating liuer disorders | TANABE SEIYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| US-4996331-A | Novel biphenyl derivative and preparation and use thereof | TSUMURA & CO. (JP) | 1991-02-26 | — | — | US | disclosed |
| US-4925872-A | HEPATITIS | TSUMURA & CO. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4849448-A | LIVER DISORDER TREATMENT | TSUMURA JUNTENDO, INC. (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0267970-A1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO. (JP) | 1988-05-25 | — | — | EP | disclosed |