Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TARBP2 | Q15633 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bifendate SCHEMBL29516235 | 0.92 | TARBP2 (0.48) | POLBKDM4ETARBP2USP2HSD17B10 | |
| Bifendate SCHEMBL896166 | 0.92 | TARBP2 (0.48) | POLBKDM4ETARBP2USP2HSD17B10 | |
| Bifendate SCHEMBL30788692 | 0.92 | TARBP2 (0.48) | POLBKDM4ETARBP2USP2HSD17B10 | |
| SCHEMBL9328107 | 0.90 | KDM4E (0.45) | POLBKDM4ETARBP2USP2HSD17B10 | |
| SCHEMBL9329569 | 0.88 | PKM (0.46) | POLBKDM4EHSD17B10CYP3A4ALOX15 | |
| SCHEMBL9327972 | 0.87 | LMNA (0.42) | POLBHSD17B10CYP3A4ALOX15GSK3B | |
| SCHEMBL9514705 | 0.87 | TARBP2 (0.64) | POLBKDM4ETARBP2USP2HSD17B10 | |
| SCHEMBL9329537 | 0.86 | TARBP2 (0.42) | POLBKDM4ETARBP2USP2HSD17B10 | |
| SCHEMBL25688023 | 0.85 | TARBP2 (0.44) | POLBKDM4ETARBP2USP2HSD17B10 | |
| SCHEMBL11929030 | 0.84 | KDM4E (0.69) | POLBKDM4EUSP2HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267970-B1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5264594-A | Alkylation of carbonates | TSUMURA & CO. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-4996331-A | Novel biphenyl derivative and preparation and use thereof | TSUMURA & CO. (JP) | 1991-02-26 | — | — | US | disclosed |
| US-4925872-A | HEPATITIS | TSUMURA & CO. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4849448-A | LIVER DISORDER TREATMENT | TSUMURA JUNTENDO, INC. (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0267970-A1 | NOVEL BIPHENYL DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE | TSUMURA & CO. (JP) | 1988-05-25 | — | — | EP | disclosed |