Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 7/20 | 0.45 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969281 | 0.90 | AVPR1A (0.51) | AVPR1AAVPR1BAVPR2TP53LMNA | |
| SCHEMBL6970232 | 0.88 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2TP53LMNA | |
| SCHEMBL9414294 | 0.86 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2TP53LMNA | |
| SCHEMBL8961732 | 0.84 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2TP53LMNA | |
| SCHEMBL6960071 | 0.84 | AVPR1A (0.53) | AVPR1AAVPR1BAVPR2ALDH1A1PDCD1 | |
| SCHEMBL6960321 | 0.84 | AVPR1A (0.52) | AVPR1AAVPR1BAVPR2TP53LMNA | |
| SCHEMBL6967087 | 0.83 | AVPR1A (0.47) | AVPR1AAVPR1BAVPR2TP53LMNA | |
| SCHEMBL6970362 | 0.82 | AVPR1A (0.49) | AVPR1AAVPR1BAVPR2ALDH1A1MAPT | |
| SCHEMBL6970821 | 0.81 | AVPR1A (0.57) | AVPR1AAVPR1BAVPR2PDCD1CD274 | |
| SCHEMBL6957577 | 0.80 | AVPR1A (0.49) | AVPR1AAVPR1BAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |