Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CTH | P32929 | 1/20 | 0.31 |
| ▸ | CBS | P35520 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9293099 | 0.89 | — | — | |
| SCHEMBL9790193 | 0.75 | — | — | |
| SCHEMBL3296616 | 0.75 | ALDH1A1 (0.38) | — | |
| SCHEMBL159233 | 0.71 | — | — | |
| SCHEMBL8961738 | 0.70 | — | — | |
| SCHEMBL9457761 | 0.69 | ALDH1A1 (0.43) | TSHR | |
| SCHEMBL721746 | 0.68 | — | — | |
| SCHEMBL757295 | 0.68 | TSHR (0.38) | TSHR | |
| SCHEMBL9457754 | 0.67 | — | — | |
| SCHEMBL3953257 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424000-B1 | Novel silicone polymers, copolymers and block copolymers and a method for their preparation | DOW CORNING (US) | 1996-02-07 | — | — | EP | disclosed |
| US-5371147-A | Silicone-containing acrylic star polymers, block copolymers and macromonomers | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-5359018-A | Group transfer polymerization using initiator and zinc, cadmium, or mercury halides and iodine as catalysts | DOW CORNING CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |
| US-5331067-A | Acrylic polymers containing trimethylsiloxy groups | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-07-19 | — | — | US | disclosed |
| US-5314961-A | Acrylic-silicone polymers | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| US-5314960-A | Silicone-containing polymers, oxygen permeable hydrophilic contact lenses and methods for making these lenses and treating patients with visual impairment | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| US-5244981-A | Acrylic polymers with pendant silicon containing groups, macromonomers, star polymers | PERMEABLE TECHNOLOGIES, INC. (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0552306-A1 | NOVEL SILICONE-CONTAINING POLYMERS AND OXYGEN PERMEABLE HYDROPHILIC CONTACT LENSES THEREFROM | PERMEABLE TECHNOLOGIES, INC. (US) | 1993-07-28 | — | — | EP | disclosed |
| US-5171809-A | Silicone-acrylate copolymer | DOW CORNING CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |
| US-5162396-A | Silicone acrylate polymers; adhesion promoters in glass reinforced polyesters | DOW CORNING CORPORATION (US) | 1992-11-10 | — | — | US | disclosed |
| US-4783500-A | ORGANO-SILICON,-TIN, OR -GERMANIUM INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-08 | — | — | US | disclosed |
| US-4711942-A | FROM ACRYLIC OR MALEIMIDE MONOMER AND ORGANOSILICON,-TIN, OR -GERMANIUM INITIATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-08 | — | — | US | disclosed |
| US-4681918-A | ACRYLIC-TYPE OR MALEIMIDE MONOMERS; ORGANOSILICON, TIN OR GERMANIUM INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-21 | — | — | US | disclosed |
| EP-0068887-B1 | \"LIVING\" POLYMERS AND PROCESS FOR THEIR PREPARATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |
| EP-0145263-A1 | Living polymers and process for their preparation | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-19 | — | — | EP | disclosed |
| US-4524196-A | Process for preparing \"living\" polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-18 | — | — | US | disclosed |
| US-4508880-A | ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANOSILICON, (-TIN, OR-GERMANIUM) INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-02 | — | — | US | disclosed |
| US-4417034-A | POLYMERIZING ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANO-SILICON, -TIN, OR-GERMANIUM INITIATORS | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-11-22 | — | — | US | disclosed |
| US-4414372-A | ADDITION POLYMERS WITH FUNCTIONAL END GROUPS | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-11-08 | — | — | US | disclosed |
| EP-0068887-A1 | \"Living\" polymers and process for their preparation | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |