SCHEMBL8961760

SCHEMBL8961760

CCCCCCCCC[Si](C)(C)Oc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.44
KCNH2 Q12809 2/20 0.42
MLNR O43193 1/20 0.42
NR1I2 O75469 1/20 0.42
ESR1 P03372 1/20 0.42
NR3C1 P04150 1/20 0.42
PGR P06401 1/20 0.42
ADRB2 P07550 1/20 0.42
CHRM2 P08172 1/20 0.42
ADRB1 P08588 1/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
CHRM1 P11229 1/20 0.42
DRD2 P14416 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
CHRM3 P20309 1/20 0.42
MAOA P21397 1/20 0.42
CNR1 P21554 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29134152 1.00 LTA4H (0.44) LTA4HKCNH2MLNRNR1I2ESR1
SCHEMBL8961710 0.98 LTA4H (0.46) LTA4HKCNH2MLNRNR1I2ESR1
SCHEMBL6987433 0.92 LTA4H (0.46) LTA4HKCNH2MLNRNR1I2ESR1
SCHEMBL706868 0.90 KCNA3 (0.41) LTA4HKCNH2DRD2DRD3LMNA
SCHEMBL703963 0.86 KCNA3 (0.41) LTA4HKCNH2DRD2DRD3LMNA
SCHEMBL7561605 0.85 LTA4H (0.44) LTA4HKCNH2MLNRNR1I2ESR1
SCHEMBL27864101 0.84 LTA4H (0.39) LTA4HKCNH2MLNRNR1I2ESR1
SCHEMBL8979064 0.83 LTA4H (0.46) LTA4HKCNH2MLNRNR1I2ESR1
SCHEMBL4810179 0.83 LTA4H (0.46) LTA4HKCNH2MLNRNR1I2ESR1
SCHEMBL958899 0.83 LTA4H (0.46) LTA4HKCNH2MLNRNR1I2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0564275-B1 Antifouling paint NIPPON PAINT CO LTD (JP) 1996-01-31 EP disclosed
US-5332431-A Alkylphenoxy group containing organosilicon compound NIPPON PAINT CO., LTD. (JP) 1994-07-26 US disclosed
EP-0564275-A1 Antifouling paint NIPPON PAINT CO., LTD. (JP) 1993-10-06 EP disclosed