SCHEMBL8961768

SCHEMBL8961768

ClC(Cl)Sc1ncncn1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10848395 0.63 HSP90AA1 (0.38) HSP90AA1
SCHEMBL7328310 0.63
SCHEMBL3725333 0.63
SCHEMBL6673910 0.63
SCHEMBL2363479 0.63
SCHEMBL9464242 0.59 HSP90AA1 (0.35) HSP90AA1
Chloroform SCHEMBL28737202 0.58 LMNA (0.40)
SCHEMBL726341 0.58
SCHEMBL2371086 0.58 HSP90AA1 (0.33) HSP90AA1
SCHEMBL9018817 0.58 MEN1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0395938-B1 Process for the preparation of 2-(2',4'-dihydroxyphenyl)-4,6-diaryl-s-triazines CIBA GEIGY AG (CH) 1996-01-17 EP disclosed
US-5106972-A 2-METHYL-THIO-4,6-DIARYL-TRIAZINES CIBA-GEIGY CORPORATION (US) 1992-04-21 US disclosed
US-5084570-A PROCESS FOR THE PREPARATION OF 2-(2',4'-DIHYDROXYPHENYL)-4,6-DIARYL-S-TRIAZINES CIBA-GEIGY CORPORATION (US) 1992-01-28 US disclosed
EP-0395938-A2 Process for the preparation of 2-(2',4'-dihydroxyphenyl)-4,6-diaryl-s-triazines CIBA-GEIGY AG (CH) 1990-11-07 EP disclosed