Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | TNFSF10 | P50591 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6309967 | 0.87 | HSP90AA1 (0.72) | RAB9ANPC1CYP1A2HTTCYP2C19 | |
| SCHEMBL11810896 | 0.83 | L3MBTL1 (0.52) | RAB9ANPC1CYP1A2HTTCYP2C19 | |
| SCHEMBL6111135 | 0.83 | L3MBTL1 (0.52) | RAB9ANPC1CYP1A2HTTCYP2C19 | |
| SCHEMBL29363934 | 0.82 | RAB9A (1.00) | RAB9ANPC1CYP1A2HTTCYP2C19 | |
| SCHEMBL2879894 | 0.81 | L3MBTL1 (0.50) | RAB9ANPC1CYP1A2HTTCYP2C19 | |
| SCHEMBL13231717 | 0.81 | L3MBTL1 (0.50) | RAB9ANPC1CYP1A2HTTCYP2C19 | |
| SCHEMBL15025989 | 0.81 | L3MBTL1 (0.50) | RAB9ANPC1CYP1A2HTTCYP2C19 | |
| SCHEMBL2876376 | 0.81 | L3MBTL1 (0.50) | RAB9ANPC1CYP1A2HTTCYP2C19 | |
| SCHEMBL25604007 | 0.80 | HSP90AA1 (0.75) | RAB9ANPC1CYP1A2HTTCYP2C19 | |
| SCHEMBL5592998 | 0.77 | MAPT (0.52) | RAB9ANPC1CYP1A2HTTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395938-B1 | Process for the preparation of 2-(2',4'-dihydroxyphenyl)-4,6-diaryl-s-triazines | CIBA GEIGY AG (CH) | 1996-01-17 | — | — | EP | disclosed |
| US-5106972-A | 2-METHYL-THIO-4,6-DIARYL-TRIAZINES | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| US-5084570-A | PROCESS FOR THE PREPARATION OF 2-(2',4'-DIHYDROXYPHENYL)-4,6-DIARYL-S-TRIAZINES | CIBA-GEIGY CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |
| EP-0395938-A2 | Process for the preparation of 2-(2',4'-dihydroxyphenyl)-4,6-diaryl-s-triazines | CIBA-GEIGY AG (CH) | 1990-11-07 | — | — | EP | disclosed |