Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 9/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA3 | P07451 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 7/20 | 0.56 |
| ▸ | ACHE | P22303 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868179 | 0.91 | XDH (0.77) | XDHCA12CA1CA2CA3 | |
| SCHEMBL8868004 | 0.88 | XDH (0.72) | XDHALDH1A1MAPTMAPK1 | |
| SCHEMBL1795058 | 0.87 | XDH (0.73) | XDHBCHEACHE | |
| SCHEMBL1793686 | 0.87 | XDH (0.56) | XDHCA12CA1CA2CA3 | |
| SCHEMBL19583388 | 0.86 | XDH (0.73) | XDHBCHEACHE | |
| SCHEMBL12240977 | 0.86 | ALDH1A1 (0.55) | XDHCA12CA1CA2CA6 | |
| SCHEMBL15003206 | 0.86 | CYP1A2 (0.62) | XDHCA12CA1CA4CA6 | |
| SCHEMBL1795724 | 0.85 | XDH (0.56) | XDHBCHEACHE | |
| SCHEMBL1794588 | 0.85 | XDH (0.54) | XDHCA12CA1CA2CA3 | |
| SCHEMBL1796407 | 0.85 | XDH (0.57) | XDHCA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516794-A | FOR THE TREATMENT OF BONE RESORPTION | INVERNI DELLA BEEFA S.P.A. (IT) | 1996-05-14 | — | — | US | claimed |
| EP-0586960-B1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA SPA (IT) | 1996-02-07 | — | — | EP | claimed |
| EP-0586960-A1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA S.P.A. (IT) | 1994-03-16 | — | — | EP | claimed |