Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 2/20 | 0.40 |
| ▸ | CDC25C | P30307 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24684634 | 0.89 | MAOB (0.56) | MAOBALDH1A1GAAHPGDCYP11B1 | |
| SCHEMBL8175559 | 0.89 | ALDH1A1 (0.55) | MAOBALDH1A1GAAHPGDNPC1 | |
| SCHEMBL31124704 | 0.89 | ALDH1A1 (0.55) | MAOBALDH1A1GAAHPGDNPC1 | |
| SCHEMBL20317331 | 0.86 | MAOB (0.48) | MAOBALDH1A1GAAHPGDCYP11B1 | |
| SCHEMBL20346703 | 0.83 | MAOB (0.48) | MAOBALDH1A1GAAHPGDCYP11B1 | |
| SCHEMBL9980172 | 0.81 | ALPG (0.53) | ALDH1A1GAAHPGDNPC1MEN1 | |
| SCHEMBL5781043 | 0.80 | MAOA (0.67) | MAOBALDH1A1HPGDCYP11B1CYP11B2 | |
| SCHEMBL2628169 | 0.80 | MAOA (0.67) | MAOBALDH1A1HPGDNPC1MEN1 | |
| SCHEMBL24726887 | 0.80 | MAOB (0.47) | MAOBALDH1A1GAAHPGDNPC1 | |
| SCHEMBL26766664 | 0.79 | MAOB (0.54) | MAOBALDH1A1GAAHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516794-A | FOR THE TREATMENT OF BONE RESORPTION | INVERNI DELLA BEEFA S.P.A. (IT) | 1996-05-14 | — | — | US | disclosed |
| EP-0586960-B1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA SPA (IT) | 1996-02-07 | — | — | EP | disclosed |
| EP-0586960-A1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA S.P.A. (IT) | 1994-03-16 | — | — | EP | disclosed |