Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962005 | 0.89 | MAOB (0.53) | MAOBMAOAKDM4EALDH1A1GLA | |
| SCHEMBL16674816 | 0.76 | MAOA (0.68) | MAOBMAOAKDM4EALDH1A1GLA | |
| 7-Cyclohexyloxycoumarin SCHEMBL14802688 | 0.75 | MAOA (0.67) | MAOBMAOAKDM4EALDH1A1GLA | |
| SCHEMBL16674814 | 0.75 | MAOB (0.65) | MAOBMAOAKDM4EALDH1A1GLA | |
| SCHEMBL8961864 | 0.72 | MEN1 (0.50) | MAOBMAOAKDM4EALDH1A1GLA | |
| SCHEMBL28918559 | 0.71 | KDM4E (0.61) | MAOBMAOAKDM4EALDH1A1GLA | |
| SCHEMBL28918558 | 0.71 | MAOA (0.61) | MAOBMAOAKDM4EALDH1A1GLA | |
| SCHEMBL31206404 | 0.71 | MAOB (0.78) | MAOBMAOAKDM4EALDH1A1GLA | |
| SCHEMBL27750354 | 0.71 | MAOB (1.00) | MAOBMAOAKDM4EALDH1A1GAA | |
| SCHEMBL8961843 | 0.70 | CA12 (0.60) | MAOBMAOAKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586960-B1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA SPA (IT) | 1996-02-07 | — | — | EP | claimed |