Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21467879 | 0.92 | TTR (0.58) | TTRCA1CA2AHRMCL1 | |
| SCHEMBL21468178 | 0.92 | TTR (0.62) | TTRCA1CA2AHRMCL1 | |
| SCHEMBL25720298 | 0.89 | AHR (0.62) | TTRCA1CA2AHRMCL1 | |
| SCHEMBL29465920 | 0.89 | TTR (0.71) | TTRCA1CA2AHRMCL1 | |
| SCHEMBL11728871 | 0.89 | TTR (0.71) | TTRCA1CA2AHRMCL1 | |
| SCHEMBL8175559 | 0.89 | ALDH1A1 (0.55) | TTRMEN1KMT2AALDH1A1GAA | |
| SCHEMBL31124704 | 0.89 | ALDH1A1 (0.55) | TTRMEN1KMT2AALDH1A1GAA | |
| SCHEMBL16477278 | 0.82 | MAPT (0.60) | TTRCA1CA2AHRMCL1 | |
| SCHEMBL9980172 | 0.81 | ALPG (0.53) | MEN1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL2628169 | 0.80 | MAOA (0.67) | TTRMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516794-A | FOR THE TREATMENT OF BONE RESORPTION | INVERNI DELLA BEEFA S.P.A. (IT) | 1996-05-14 | — | — | US | disclosed |
| EP-0586960-B1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA SPA (IT) | 1996-02-07 | — | — | EP | disclosed |
| EP-0586960-A1 | Xanthone derivatives, their preparation and use | INVERNI DELLA BEFFA S.P.A. (IT) | 1994-03-16 | — | — | EP | disclosed |