Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Betaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Betaine SCHEMBL2231700 | 1.00 | HTT (0.46) | HTTDNM1TSHRALDH1A1LMNA | |
| Betaine SCHEMBL2235072 | 1.00 | HTT (0.46) | HTTDNM1TSHRALDH1A1LMNA | |
| Betaine SCHEMBL2230085 | 1.00 | HTT (0.46) | HTTDNM1TSHRALDH1A1LMNA | |
| Betaine SCHEMBL2232251 | 0.91 | TSHR (0.42) | DNM1TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL8028213 | 0.87 | DNM1 (0.40) | DNM1TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL8028207 | 0.87 | DNM1 (0.40) | DNM1TSHRALDH1A1LMNAAPEX1 | |
| SCHEMBL60618 | 0.87 | HTT (0.60) | HTTDNM1LMNAENPP2KMT2A | |
| SCHEMBL16604562 | 0.87 | HTT (0.60) | HTTDNM1LMNAENPP2KMT2A | |
| SCHEMBL10933953 | 0.87 | HTT (0.60) | HTTDNM1LMNAENPP2KMT2A | |
| SCHEMBL9691972 | 0.87 | HTT (0.60) | HTTDNM1LMNAENPP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765658-B1 | ELECTROPLATED PRODUCTS AND ELECTROPLATING BATH FOR PROVIDING SUCH PRODUCTS | COVENTYA S P A (IT) | 2023-06-14 | — | — | EP | claimed |
| EP-3540097-A1 | ELECTROPLATED PRODUCTS AND ELECTROPLATING BATH FOR PROVIDING SUCH PRODUCTS | COVENTYA S.p.A. (IT) | 2019-09-18 | — | — | EP | claimed |
| EP-4244409-A1 | METHOD FOR PREPARING AN ELECTROPLATED PRODUCT BY DEPOSITING AN UNDERLAYER, DIFFUSION BARRIER LAYER AND TOP LAYER ON THE SURFACE OF A SUBSTRATE AND SUCH PREPARED ELECTROPLATED PRODUCT | COVENTYA S.p.A. (IT) | 2023-09-20 | — | — | EP | disclosed |
| EP-3765658-B1 | ELECTROPLATED PRODUCTS AND ELECTROPLATING BATH FOR PROVIDING SUCH PRODUCTS | COVENTYA S P A (IT) | 2023-06-14 | — | — | EP | disclosed |
| EP-4001472-A1 | METHOD FOR PREPARING AN ELECTROPLATED PRODUCT BY DEPOSITING AN UNDERLAYER, DIFFUSION BARRIER LAYER AND TOP LAYER ON THE SURFACE OF A SUBSTRATE AND SUCH PREPARED ELECTROPLATED PRODUCT | COVENTYA S.p.A. (IT) | 2022-05-25 | — | — | EP | disclosed |
| WO-2022101474-A1 | METHOD FOR PREPARING AN ELECTROPLATED PRODUCT BY DEPOSITING AN UNDERLAYER, DIFFUSION BARRIER LAYER AND TOP LAYER ON THE SURFACE OF A SUBSTRATE AND SUCH PREPARED ELECTROPLATED PRODUCT | COVENTYA S.P.A. (IT) | 2022-05-19 | — | — | WO | disclosed |
| EP-3765658-A1 | ELECTROPLATED PRODUCTS AND ELECTROPLATING BATH FOR PROVIDING SUCH PRODUCTS | COVENTYA S.p.A. (IT) | 2021-01-20 | — | — | EP | disclosed |
| US-20200385603-A1 | Composition for Encapsulation and Containment of Substances | Tru BLOC LLC (US) | 2020-12-10 | — | — | US | disclosed |
| US-10752800-B2 | Composition for encapsulation and containment of substances | Tru BLOC LLC (US) | 2020-08-25 | — | — | US | disclosed |
| EP-3540097-A1 | ELECTROPLATED PRODUCTS AND ELECTROPLATING BATH FOR PROVIDING SUCH PRODUCTS | COVENTYA S.p.A. (IT) | 2019-09-18 | — | — | EP | disclosed |
| US-20190055424-A1 | Composition for Encapsulation and Containment of Substances | Tru BLOC LLC (US) | 2019-02-21 | — | — | US | disclosed |
| US-5585472-A | CATALYTIC REACTION OF ALCOHOLS WITH MONOSACCHARIDES USING ACID FORM OF AMPHOTERIC SURFACTANTS AS CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-4381980-A | FROM AN N-SUBSTITUTED ALLYLAMMONIUM COMPOUND BY CATALYTIC SULFONATION WITH SULFUROUS ACID SALT | AKADEMIE DER WISSENSCHAFTEN DER DDR (DD) | 1983-05-03 | — | — | US | disclosed |