Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MDM4 | O15151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31045285 | 0.82 | IDO1 (0.56) | L3MBTL1ALDH1A1HPGDMDM4TP53 | |
| SCHEMBL11427682 | 0.82 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1HPGDMDM4TP53 | |
| SCHEMBL2635669 | 0.82 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1HPGDMDM4TP53 | |
| SCHEMBL3150784 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDPOLBTSHRNPC1 | |
| SCHEMBL30168125 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDPOLBTSHRNPC1 | |
| SCHEMBL3026540 | 0.79 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1MDM4TP53CETP | |
| SCHEMBL8930723 | 0.78 | HPGD (0.61) | ALDH1A1HPGDPOLBNPC1RAB9A | |
| SCHEMBL8930764 | 0.77 | KMT2A (0.56) | ALDH1A1HPGDPOLBTAS1R3TAS1R1 | |
| SCHEMBL2449426 | 0.77 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1HPGDPOLBNPC1 | |
| SCHEMBL8930775 | 0.74 | POLB (0.58) | ALDH1A1POLBTSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188203-B2 | Intraocular lens formed from a polymer of an unsaturated aryl monoazo dye containing a 2-pyrazolin-5-one, dimedone (5,5-dimethyl-1,3-cyclohexanedione), acetoacetamide, malonamide, barbituric acid or 1,3-propanedione residue; yellow light absorbers; block ultraviolet and/or violet-blue light transmission | Abbott Medical Optics Inc. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20080182957-A1 | Copolymerizable azo compounds and articles containing them | Johnson & Johnson Surgical Vision, Inc. | 2008-07-31 | — | — | US | disclosed |
| US-7326423-B2 | Copolymerizable azo compounds and articles containing them | ADVANCED MEDICAL OPTICS, INC. (US) | 2008-02-05 | — | — | US | disclosed |